Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903753 | 0.80 | SLC9A1 (0.63) | SLC9A1 | |
| Rimeporide SCHEMBL30309010 | 0.70 | SLC9A1 (1.00) | SLC9A1 | |
| Rimeporide SCHEMBL1019633 | 0.70 | SLC9A1 (1.00) | SLC9A1 | |
| Rimeporide SCHEMBL1022632 | 0.69 | SLC9A1 (0.97) | SLC9A1 | |
| Rimeporide SCHEMBL29406681 | 0.69 | SLC9A1 (0.97) | SLC9A1 | |
| Rimeporide SCHEMBL16712399 | 0.69 | SLC9A1 (0.97) | SLC9A1 | |
| SCHEMBL7119046 | 0.68 | SLC9A1 (0.40) | SLC9A1L3MBTL1 | |
| Rimeporide SCHEMBL1020614 | 0.68 | SLC9A1 (0.94) | SLC9A1 | |
| SCHEMBL7119052 | 0.64 | GRIA1 (0.47) | SLC9A1L3MBTL1 | |
| SCHEMBL12516764 | 0.64 | HTR3E (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1098866-B1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK PATENT GMBH (DE) | 2004-02-11 | — | — | EP | disclosed |
| US-6573404-B2 | Intermediates in industrial organic synthesis, e.g. in the preparation of fine chemicals, dyes and crop-protection compositions | MERCK PATENT GMBH (DE) | 2003-06-03 | — | — | US | disclosed |
| US-20030069444-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | MERCK KGAA (DE) | 2003-04-10 | — | — | US | disclosed |
| US-6515143-B2 | 2-bromo-5-chlorotoluene is reacted with a secondary or tertiary organolithium compound, and carbon dioxide to give 4-chloro-2-methylbenzoic acid | MERCK KGAA (DE) | 2003-02-04 | — | — | US | disclosed |
| US-20020091286-A1 | Method for producing ortho-alkylated benzoic acid derivatives | MERCK GMBH (DE) | 2002-07-11 | — | — | US | disclosed |
| US-6350904-B1 | CATALYTIC CARBOXYLATION OF HALOALKYLBENZENE | MERCK KGAA (DE) | 2002-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091286-A1 | Method for producing ortho-alkylated benzoic acid derivatives | AOC2, OXER1, GABBR2 | SLC9A1 2216/4885L3MBTL1 4404/4885 |
| US-20030069444-A1 | METHOD FOR PRODUCING ORTHO-ALKYLATED BENZOIC ACID DERIVATIVES | AOC2, OXER1, GABBR2 | SLC9A1 2216/4885L3MBTL1 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.