SCHEMBL6901227

SCHEMBL6901227

c1ccc(Cc2ccc3c(c2)Cc2ccccc2C3)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.50
IDH1 O75874 1/20 0.48
PARP11 Q9NR21 1/20 0.46
HNF4A P41235 1/20 0.42
LTA4H P09960 2/20 0.41
HTR2A P28223 1/20 0.40
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
ATM Q13315 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
PDK2 Q15119 1/20 0.39
PRSS1 P07477 1/20 0.39
PRSS2 P07478 1/20 0.39
PRSS3 P35030 1/20 0.39
TACR1 P25103 1/20 0.38
TACR3 P29371 1/20 0.38
PLA2G10 O15496 1/20 0.38
PLA2G2A P14555 1/20 0.38
LMNA P02545 1/20 0.38
NPC1 O15118 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31040985 0.88 PARP11 (0.54) CALM1IDH1PARP11HNF4ATSHR
SCHEMBL3974006 0.86 TSHR (0.54) CALM1IDH1PARP11TSHRALDH1A1
SCHEMBL3982676 0.82 ALDH1A1 (0.47) CALM1IDH1PARP11TSHRALDH1A1
SCHEMBL598903 0.79 TSHR (0.58) TSHRALDH1A1ATMNPSR1LMNA
SCHEMBL5675962 0.79 PARP11 (0.50) CALM1IDH1PARP11HNF4ATSHR
SCHEMBL28375633 0.79 CALM1 (0.44) CALM1IDH1PARP11HNF4ALTA4H
SCHEMBL6901854 0.78 MAOA (0.57) CALM1IDH1PARP11HNF4ALMNA
SCHEMBL27791814 0.78 PARP11 (0.49) CALM1IDH1PARP11TSHRALDH1A1
SCHEMBL16721093 0.77 PARP11 (0.43) CALM1IDH1PARP11HTR2ATSHR
SCHEMBL28384978 0.77 PARP11 (0.42) CALM1IDH1PARP11PDK2TACR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed