Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | FOS | P01100 | 1/20 | 0.47 |
| ▸ | JUN | P05412 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30436820 | 0.88 | HSD17B10 (0.71) | POLBHSD17B10MTNR1AMTNR1BADRA1A | |
| SCHEMBL491188 | 0.88 | HSD17B10 (0.71) | POLBHSD17B10MTNR1AMTNR1BADRA1A | |
| SCHEMBL6902374 | 0.83 | ELANE (0.47) | POLBELANEFOSJUNKDM4E | |
| SCHEMBL11706717 | 0.81 | KDM4E (0.50) | MTNR1AMTNR1BALDH1A1BACE1KDM4E | |
| SCHEMBL9854773 | 0.81 | MTNR1B (0.54) | HSD17B10MTNR1AMTNR1BBACE1HPGD | |
| SCHEMBL6902841 | 0.81 | FFAR1 (0.51) | POLBELANEALDH1A1FOSJUN | |
| SCHEMBL7368806 | 0.80 | POLB (0.79) | POLBHSD17B10MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL7369145 | 0.79 | POLB (0.63) | POLBHSD17B10MTNR1AMTNR1BALDH1A1 | |
| SCHEMBL10908806 | 0.79 | ALDH1A1 (0.50) | HSD17B10MTNR1AMTNR1BALDH1A1BACE1 | |
| SCHEMBL11433418 | 0.79 | HSD17B10 (0.67) | POLBHSD17B10MTNR1AMTNR1BADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596828-A | Topical | MERCK & CO., INC. (US) | 1986-06-24 | — | — | US | disclosed |