Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.72 |
| ▸ | CA9 | Q16790 | 1/20 | 0.72 |
| ▸ | ACHE | P22303 | 11/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | TARDBP | Q13148 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522023 | 1.00 | CA12 (0.72) | CA12CA9ACHEHSD17B10KMT2A | |
| Imidazole SCHEMBL7842242 | 0.86 | CA12 (0.56) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL13834757 | 0.86 | CA12 (0.74) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL14299002 | 0.85 | CA12 (0.60) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL7839737 | 0.84 | ACHE (0.75) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL8506206 | 0.84 | CA12 (0.64) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL8507030 | 0.84 | CA12 (0.64) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL7843204 | 0.83 | CA12 (0.67) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL2379525 | 0.83 | CA12 (0.66) | CA12CA9ACHEHSD17B10KMT2A | |
| SCHEMBL14669959 | 0.83 | CA12 (0.66) | CA12CA9ACHEHSD17B10KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040018996-A1 | Unit dosage forms for the treatment of herpes simplex | CHRONORX, LLC (US) | 2004-01-29 | — | — | US | claimed |
| US-6524619-B2 | Interdependent biofactors and biomolecules, such as minerals, vitamins and antioxidants and their clinically useful formulations for support of endothelial physiology of the inner ear | CHRONORX, INC. | 2003-02-25 | — | — | US | claimed |
| US-20020197313-A1 | Unit dosage forms for the treatment of herpes simplex | CHRONORX, LLC (US) | 2002-12-26 | — | — | US | claimed |
| US-20010031737-A1 | Unit dosage forms for the treatment of herpes simplex | RICHARDSON KENNETH T (US) | 2001-10-18 | — | — | US | claimed |
| US-6231889-B1 | THIOL GLUTATHIONE WITH METALS | CHRONORX, LLC | 2001-05-15 | — | — | US | claimed |
| US-6207190-B1 | SYNERGISTIC MIXTURE TO REDUCE OCULAR PRESSURE AND IMPROVE VASCULAR HEALTH COMPRISING FOLIC ACID, A MAGNESIUM SALT, ALPHA-TOCOPHEROL, ASCORBATE AND ALPHA-LIPOIC ACID | CHRONORX, LLC | 2001-03-27 | — | — | US | claimed |
| EP-4282411-A1 | LIPOYL-GLU-ALA FOR THE TREATMENT OF NEURODEGENERATIVE DAMAGE CAUSED BY TRAUMATIC BRAIN INJURY | Ischemix LLC (US) | 2023-11-29 | — | — | EP | disclosed |
| WO-2023065550-A1 | POLYDISULFIDE POLYPEPTIDE NANOPARTICLE, PREPARATION METHOD THEREFOR, AND POLYPEPTIDE DRUG ORAL PREPARATION | 福州大学 | 2023-04-27 | — | — | WO | disclosed |
| US-11213509-B2 | Compositions and methods for treating traumatic brain injury | Ischemix, LLC (US) | 2022-01-04 | — | — | US | disclosed |
| US-20200352904-A1 | Compositions And Methods For Treating Traumatic Brain Injury | ISCHEMIX LLC | 2020-11-12 | — | — | US | disclosed |
| US-10744115-B2 | Compositions and methods for treating traumatic brain injury | ISCHEMIX LLC (US) | 2020-08-18 | — | — | US | disclosed |
| EP-2640423-B1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | ISCHEMIX LLC (US) | 2017-07-26 | — | — | EP | disclosed |
| US-9359325-B2 | Lipoyl compounds and methods for treating ischemic injury | ISCHEMIX LLC (US) | 2016-06-07 | — | — | US | disclosed |
| US-8815937-B2 | Lipoyl compounds and their use for treating ischemic injury | ISCHEMIX LLC (US) | 2014-08-26 | — | — | US | disclosed |
| US-20130237483-A1 | Lipoyl Compounds And Their Use for Treating Ischemic Injury | ISCHEMIX LLC | 2013-09-12 | — | — | US | disclosed |
| US-20130237483-A1 | Lipoyl Compounds And Their Use for Treating Ischemic Injury | ISCHEMIX LLC | 2013-09-12 | — | — | US | disclosed |
| WO-2012067947-A1 | LIPOYL COMPOUNDS AND THEIR USE FOR TREATING ISCHEMIC INJURY | ISCHEMIX LLC (US) | 2012-05-24 | — | — | WO | disclosed |
| US-6524619-B2 | Interdependent biofactors and biomolecules, such as minerals, vitamins and antioxidants and their clinically useful formulations for support of endothelial physiology of the inner ear | CHRONORX, INC. | 2003-02-25 | — | — | US | disclosed |
| US-20020061870-A1 | Dosage forms useful for modifying conditions and functions associated with hearing loss and/or tinnitus | CHRONORX, LLC | 2002-05-23 | — | — | US | disclosed |
| US-6207190-B1 | SYNERGISTIC MIXTURE TO REDUCE OCULAR PRESSURE AND IMPROVE VASCULAR HEALTH COMPRISING FOLIC ACID, A MAGNESIUM SALT, ALPHA-TOCOPHEROL, ASCORBATE AND ALPHA-LIPOIC ACID | CHRONORX, LLC | 2001-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11213509-B2 | Compositions and methods for treating traumatic brain injury | BDNF, NLN, FABP7 | CA12 2801/4885CA9 3690/4885ACHE 8/4885 |
| US-20200352904-A1 | Compositions And Methods For Treating Traumatic Brain Injury | BDNF, NLN, FABP7 | CA12 2801/4885CA9 3690/4885ACHE 8/4885 |
| US-10744115-B2 | Compositions and methods for treating traumatic brain injury | BDNF, NLN, FABP7 | CA12 2801/4885CA9 3690/4885ACHE 8/4885 |
| US-20130237483-A1 | Lipoyl Compounds And Their Use for Treating Ischemic Injury | CPT1A, LIPG, LIPC | CA12 2901/4885CA9 1601/4885ACHE 2328/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.