Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 3/20 | 0.46 |
| ▸ | CCR5 | P51681 | 3/20 | 0.46 |
| ▸ | CCR8 | P51685 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | METAP1 | P53582 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.46 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13400768 | 0.84 | KDM4E (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL27336608 | 0.74 | KDM4E (0.42) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL7608467 | 0.74 | HTR6 (0.31) | — | |
| Fluorene SCHEMBL27950409 | 0.72 | KDM4E (0.61) | KDM4ELMNACCR1CCR5CCR8 | |
| Fluorene SCHEMBL27530322 | 0.71 | KDM4E (0.52) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL858806 | 0.70 | KDM4E (0.72) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL170839 | 0.70 | ALDH1A1 (0.39) | KDM4ELMNANPC1RAB9ASMN1; SMN2 | |
| Dipyridyl SCHEMBL1571842 | 0.70 | KDM4E (0.93) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL12853975 | 0.68 | KDM4E (0.68) | KDM4ELMNACCR1CCR5CCR8 | |
| SCHEMBL29723140 | 0.68 | KDM4E (0.68) | KDM4ELMNACCR1CCR5CCR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101784529-A | Urea and carbamate derivatives as non-nucleoside reverse transcriptase inhibitors | HOFFMANN LA ROCHE | 2010-07-21 | — | — | CN | claimed |
| CN-100357326-C | Process for preparing aqueous dye-containing polymer dispersions | BASF AG (DE) | 2007-12-26 | — | — | CN | claimed |
| CN-1671651-A | N-bisaryl- and N-aryl-cycloalkylidenyl-alpha-hydroxy-and alpha-alkoxy acid amides | SYNGENTA PARTICIPATIONS AG (CH) | 2005-09-21 | — | — | CN | claimed |
| CN-1520398-A | Novel N-isaryl-and N-aryl-cycloalkylidenyl-G(a)-sulfin-and G(a)-sulfonamino acid amides | �����ɷ� | 2004-08-11 | — | — | CN | claimed |
| CN-1293680-A | Method for producing aqueous polymer dispersions containing colorants | BASF AG (DE) | 2001-05-02 | — | — | CN | claimed |
| US-11584726-B2 | Amino alcohol derivative, pharmaceutical composition and application thereof | BEIJING FORELAND PHARMA CO., LTD. (CN) | 2023-02-21 | — | — | US | disclosed |
| US-20210347745-A1 | AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | BEIJING FORELAND PHARMA CO., LTD. (CN) | 2021-11-11 | — | — | US | disclosed |
| EP-3647309-A1 | AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Beijing Foreland Pharma Co., Ltd. (CN) | 2020-05-06 | — | — | EP | disclosed |
| CN-102001989-B | Heteroarylamine compounds, organic light-emitting devices and panel display devices | SAMSUNG MOBILE DISPLAY CO LTD | 2014-08-20 | — | — | CN | disclosed |
| CN-102001987-B | Heteroarylamine compound, organic light-emitting device and panel display device | SAMSUNG SDI CO LTD | 2013-05-22 | — | — | CN | disclosed |
| CN-102448958-A | Pyrimidinyl and 1,3, 5-triazinyl benzimidazole sulfonamides and their use in the treatment of cancer | PATHWAY THERAPEUTICS LTD | 2012-05-09 | — | — | CN | disclosed |
| CN-101360745-B | 8-azabicyclo[3.2.1]octane derivatives useful as monoamine reuptake inhibitors | N.V. ORGANON (NL) | 2011-12-14 | — | — | CN | disclosed |
| CN-1520398-A | Novel N-isaryl-and N-aryl-cycloalkylidenyl-G(a)-sulfin-and G(a)-sulfonamino acid amides | �����ɷ� | 2004-08-11 | — | — | CN | disclosed |
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-6458982-B1 | CATALYST SYSTEM COMPRISING AT LEAST ONE METALLOCENE AND AT LEAST ONE COCATALYST. ON SUPPORT. | TARGOR GMBH (DE) | 2002-10-01 | — | — | US | disclosed |
| CN-1308606-A | Sulfur-substituted sulfonylaminocarboxylic acid N-arylamides, their preparation, their use and pharmaceutical preparations comprising them | AVENTIS PHARMACEUTICALS AG (DE) | 2001-08-15 | — | — | CN | disclosed |
| CN-1293680-A | Method for producing aqueous polymer dispersions containing colorants | BASF AG (DE) | 2001-05-02 | — | — | CN | disclosed |
| EP-1033371-A1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | TARGOR GmbH (DE) | 2000-09-06 | — | — | EP | disclosed |
| CN-1145075-A | Antagonist's of endothelin receptors | JAPAT LTD (CH) | 1997-03-12 | — | — | CN | disclosed |
| CN-1087781-A | Plant growth regulator | UNION OIL CO (US) | 1994-06-15 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210347745-A1 | AMINO ALCOHOL DERIVATIVE, PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | SSB, HLA-DRB1, LCP2 | KDM4E 1161/4885LMNA 438/4885CCR1 374/4885 |
| US-11584726-B2 | Amino alcohol derivative, pharmaceutical composition and application thereof | SSB, HLA-DRB1, LCP2 | KDM4E 1161/4885LMNA 438/4885CCR1 374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.