Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13330632 | 0.77 | SIGMAR1 (0.43) | SIGMAR1KDM1AMAOBGRIN1GRIN2A | |
| SCHEMBL8865243 | 0.76 | TSHR (0.38) | KDM1AMAOBHDAC9TSHRTDP1 | |
| SCHEMBL6131337 | 0.75 | TSHR (0.41) | SIGMAR1CHRM1KDM1ATSHRTDP1 | |
| SCHEMBL9340819 | 0.75 | APP (0.40) | SIGMAR1OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL5871752 | 0.75 | CYP3A4 (0.57) | KDM1AMAOBHDAC9ADORA3TSHR | |
| SCHEMBL742433 | 0.74 | MAPK1 (0.38) | SIGMAR1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9531758 | 0.73 | TSHR (0.40) | SIGMAR1KDM1AMAOBHDAC9TSHR | |
| SCHEMBL5796055 | 0.73 | HDAC9 (0.50) | SIGMAR1KDM1AMAOBHDAC9TSHR | |
| SCHEMBL3053835 | 0.73 | KDM1A (0.43) | CHRM2CHRM4CHRM5CHRM1CHRM3 | |
| SCHEMBL19130584 | 0.73 | HDAC9 (0.50) | SIGMAR1KDM1AMAOBHDAC9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | disclosed |
| US-6458982-B1 | CATALYST SYSTEM COMPRISING AT LEAST ONE METALLOCENE AND AT LEAST ONE COCATALYST. ON SUPPORT. | TARGOR GMBH (DE) | 2002-10-01 | — | — | US | disclosed |
| EP-1033371-A1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | TARGOR GmbH (DE) | 2000-09-06 | — | — | EP | disclosed |