Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.30 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6901735 | 0.89 | ALDH1A1 (0.33) | TGFBR1TDP1MEN1NPC1RAB9A | |
| SCHEMBL6903610 | 0.87 | PKM (0.40) | TGFBR1TP53MAPTGAATDP1 | |
| SCHEMBL6895367 | 0.87 | TGFBR1 (0.38) | TGFBR1TP53MAPTTDP1CHRM2 | |
| SCHEMBL6903067 | 0.85 | NPC1 (0.34) | MAPTTDP1NPC1TSHRRAB9A | |
| SCHEMBL6901820 | 0.85 | PKM (0.32) | TP53MAPTGAAMEN1NPC1 | |
| SCHEMBL6902565 | 0.84 | CCR1 (0.32) | — | |
| SCHEMBL6900002 | 0.84 | TRPV1 (0.39) | MAPTTNKS2MEN1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6903521 | 0.84 | TGFBR1 (0.39) | TGFBR1TP53MAPTGAARXFP1 | |
| SCHEMBL6902284 | 0.83 | KDM4E (0.43) | TP53MAPTTDP1HTTMEN1 | |
| SCHEMBL6895444 | 0.82 | CYP1A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1033371-B1 | Transition metal compound, catalyst system, process for the preparation thereof and its use for the polymerization of olefins | BASELL POLYOLEFINE GMBH (DE) | 2004-01-28 | — | — | EP | claimed |