Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.59 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.59 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.59 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.59 |
| ▸ | RXRA | P19793 | 1/20 | 0.54 |
| ▸ | RXRB | P28702 | 1/20 | 0.54 |
| ▸ | RXRG | P48443 | 1/20 | 0.54 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.48 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.48 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14646221 | 0.86 | CSNK2A2 (0.76) | CSNK2A2CSNK2A1CSNK2BNR1H4 | |
| SCHEMBL11599027 | 0.86 | CSNK2A2 (0.76) | CSNK2A2CSNK2A1CSNK2BNR1H4 | |
| SCHEMBL22116988 | 0.84 | CSNK2A2 (0.59) | CSNK2A2CSNK2A1CSNK2BRXRARXRB | |
| SCHEMBL8840153 | 0.84 | HDAC1 (0.49) | CSNK2A2CSNK2A1CSNK2BSRD5A2KDM4E | |
| SCHEMBL505133 | 0.82 | SRD5A2 (0.77) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL5203797 | 0.82 | ALDH1A1 (0.51) | CSNK2A2CSNK2A1KDM4EMEN1ALDH1A1 | |
| SCHEMBL17656010 | 0.81 | CSNK2A2 (0.69) | CSNK2A2CSNK2A1CSNK2BNR1H4KDM4E | |
| SCHEMBL7218452 | 0.81 | CSNK2A1 (0.55) | CSNK2A2CSNK2A1SRD5A2RXRARXRB | |
| Hydrochloric Acid SCHEMBL5313295 | 0.81 | SRD5A2 (0.74) | SRD5A2RXRARXRBRXRGCYP2C8 | |
| SCHEMBL78879 | 0.80 | SRD5A2 (0.87) | SRD5A2RXRARXRBRXRGCYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1405636-A1 | FUNCTION REGULATOR FOR RETINOID RELATIVE RECEPTOR | Takeda Chemical Industries, Ltd. (JP) | 2004-04-07 | — | — | EP | disclosed |