SCHEMBL6902685

SCHEMBL6902685

CCO[SiH](OCC)c1ccccc1Cl

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.36
TSHR P16473 1/20 0.36
PNMT P11086 1/20 0.35
L3MBTL1 Q9Y468 3/20 0.34
IDO1 P14902 3/20 0.32
SLC6A2 P23975 1/20 0.32
SLC6A4 P31645 1/20 0.32
SLC6A3 Q01959 1/20 0.32
AOC3 Q16853 1/20 0.32
CASP1 P29466 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
KDM4E B2RXH2 1/20 0.32
POLB P06746 1/20 0.32
KDM1A O60341 1/20 0.32
RCOR1 Q9UKL0 1/20 0.32
DPP4 P27487 1/20 0.31
GAA P10253 1/20 0.31
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2961096 0.84 ALDH1A1 (0.33) TSHRALDH1A1
SCHEMBL103756 0.77 TSHR (0.38) TSHRGAAALDH1A1
SCHEMBL1263437 0.76 TSHR (0.32) LMNATSHRL3MBTL1ALDH1A1
SCHEMBL27999141 0.75 ALDH1A1 (0.45) TSHRL3MBTL1CASP1MEN1KMT2A
SCHEMBL27897097 0.75 L3MBTL1 (0.39) LMNAL3MBTL1IDO1AOC3KDM4E
SCHEMBL4267871 0.75 MAPT (0.40) TSHRL3MBTL1
SCHEMBL19809215 0.75 CA2 (0.38) LMNATSHRL3MBTL1IDO1MEN1
SCHEMBL6564384 0.75
SCHEMBL28038676 0.73 CA1 (0.46) LMNATSHRL3MBTL1IDO1AOC3
SCHEMBL6751506 0.72 HPGD (0.35) LMNAKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6515085-B1 Catalysts for the polymerization of alpha olefins consisting of the product of reaction of the following components: a) An Al trialkyl or an Al alkyl compound containing 2 or more Al atoms linked to each other through an oxygen or nitrogen atom BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-02-04 US claimed
EP-0179303-B2 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Himont Incorporated (US) 1992-06-17 EP claimed
EP-0147053-B1 A CATALYST AND A PROCESS FOR POLYMERIZATION OF OLEFINS Tonen Corporation (JP) 1990-09-05 EP claimed
EP-0179303-B1 CATALYSTS FOR THE POLYMERIZATION OF OLEFINS Himont Incorporated (US) 1989-05-24 EP claimed
EP-0145368-B1 PROCESS FOR PRODUCING PROPYLENE BLOCK COPOLYMERS TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1989-03-08 EP claimed
EP-0179303-A1 Catalysts for the polymerization of olefins Himont Incorporated (US) 1986-04-30 EP claimed
US-4565798-A COORDINATION CATALYSTS, TITANIUM, MAGNESIUM, SILICON COMPOUND TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1986-01-21 US claimed
EP-0147053-A1 A catalyst and a process for polymerization of olefins Tonen Corporation (JP) 1985-07-03 EP claimed
EP-0145368-A2 Process for producing propylene block copolymers TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1985-06-19 EP claimed
US-6777508-B1 HIGHLY ACTIVE AND HIGHLY STEREOSPECIFIC CATALYSTS FOR THE POLYMERIZATION OF PROPYLENE AND HIGHER OLEFINS BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2004-08-17 US disclosed
US-6515085-B1 Catalysts for the polymerization of alpha olefins consisting of the product of reaction of the following components: a) An Al trialkyl or an Al alkyl compound containing 2 or more Al atoms linked to each other through an oxygen or nitrogen atom BASELL POLIOLEFINE ITALIA S.P.A. (IT) 2003-02-04 US disclosed
US-6194342-B1 COMPRISING REACTION PRODUCT OF ALUMINUM ALKYL COMPOUND, A SILICON COMPOUND CONTAINING ONE SI--OR OR SI--OCOR OR SI--NR2 BOND, R BEING HYDROCARBYL RADICAL, A SOLID COMPRISING AS SUPPORT A MAGNESIUM DIHALIDE AND A TITANIUM HALIDE MONTELL TECHNOLOGY COMPANY BV (NL) 2001-02-27 US disclosed
EP-0646605-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1999-06-02 EP disclosed
EP-0589474-B1 Components and catalysts for the polymerization of olefins MONTELL NORTH AMERICA INC (US) 1997-05-02 EP disclosed
EP-0086471-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1983-08-24 EP disclosed
EP-0086473-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1983-08-24 EP disclosed
EP-0086472-A2 Catalyst for the polymerization of olefins Montedison S.p.A. (IT) 1983-08-24 EP disclosed
EP-0045976-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1982-02-17 EP disclosed
EP-0045977-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1982-02-17 EP disclosed
EP-0045975-A2 Components and catalysts for the polymerization of olefins Montedison S.p.A. (IT) 1982-02-17 EP disclosed