SCHEMBL6902816

SCHEMBL6902816

O=C1c2ccccc2Cc2cccc(Cl)c21

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.61
CES1 P23141 2/20 0.52
BCHE P06276 1/20 0.52
ALDH1A1 P00352 4/20 0.44
ADORA2A P29274 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
MAPT P10636 2/20 0.44
USP2 O75604 1/20 0.44
HPN P05981 1/20 0.44
CYP3A4 P08684 1/20 0.44
ALOX5 P09917 1/20 0.44
THRB P10828 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
PTGS1 P23219 1/20 0.44
PDE4A P27815 1/20 0.44
KDR P35968 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29522447 1.00 MAOA (0.61) MAOACES1BCHEALDH1A1ADORA2A
Anthracene SCHEMBL28843478 0.92 MAOA (0.52) MAOACES1BCHEALDH1A1ADORA2A
SCHEMBL7103871 0.86 TSHR (0.57) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL3787825 0.84 MAOA (0.46) MAOACES1BCHEALDH1A1MEN1
SCHEMBL769934 0.84 MAOA (0.71) MAOACES1BCHEALDH1A1CYP1A2
SCHEMBL7029795 0.84 NSD2 (0.40) MAOACES1BCHEALDH1A1ADORA2A
SCHEMBL6906371 0.83 METAP1 (0.54) MAOAALDH1A1CYP1A2MEN1KMT2A
SCHEMBL9122027 0.82 MAOA (0.57) MAOACES1BCHEALDH1A1ADORA2A
SCHEMBL28378453 0.80 MAOA (0.53) MAOACES1BCHEALDH1A1ADORA2A
SCHEMBL4652610 0.78 MAOA (0.61) MAOACES1BCHEALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1168652-A Radiation-curable organopolysiloxane release compositions AVERY DENNISON CORP (US) 1997-12-24 CN claimed
CN-115093314-B Method for synthesizing 4-chloroanthrone by taking anthrone and chlorine source as raw materials 中钢集团南京新材料研究院有限公司 2024-01-26 CN disclosed
CN-115093314-A Method for synthesizing 4-chloroanthrone by taking anthrone and chlorine source as raw materials 中钢集团南京新材料研究院有限公司 2022-09-23 CN disclosed
CN-109843825-B Coated panel and method for manufacturing coated panel 扎伊罗技术股份公司 2022-01-28 CN disclosed
CN-106489100-B Photosensitive resin composition, cured product, black matrix, and image display device 三菱化学株式会社 2020-04-03 CN disclosed
CN-106488941-B Resin, photosensitive resin composition, cured product, color filter, and image display device 三菱化学株式会社 2019-12-10 CN disclosed
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed
US-5434264-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1995-07-18 US disclosed
US-5300642-A α, α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1994-04-05 US disclosed
EP-0311010-B1 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers DU PONT MERCK PHARMA (US) 1994-02-02 EP disclosed
EP-0532054-A1 Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1993-03-17 EP disclosed
US-5173489-A α,α-disubstituted aromatics and heteroaromatics as cognition enhancers THE DUPONT MERCK PHARMACEUTICAL CO. (US) 1992-12-22 US disclosed
EP-0311010-A2 Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) 1989-04-12 EP disclosed