Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | HPN | P05981 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902816 | 0.84 | MAOA (0.61) | NSD2ADORA2AAHRMAOAMEN1 | |
| SCHEMBL9270180 | 0.84 | MAOA (0.61) | AHRMAOAMEN1ALDH1A1MAPT | |
| SCHEMBL29522447 | 0.84 | MAOA (0.61) | NSD2ADORA2AAHRMAOAMEN1 | |
| SCHEMBL10692508 | 0.83 | KDM4E (0.47) | MEN1ALDH1A1MAPTKMT2AUSP2 | |
| SCHEMBL9272968 | 0.81 | CES1 (0.44) | NSD2AHRMAOAMEN1ALDH1A1 | |
| SCHEMBL7103871 | 0.81 | TSHR (0.57) | NSD2AHRMAOAMEN1ALDH1A1 | |
| Anthracene SCHEMBL28843478 | 0.77 | MAOA (0.52) | ADORA2AMAOAMEN1ALDH1A1MAPT | |
| SCHEMBL3903366 | 0.77 | ADORA2A (0.36) | NSD2ADORA2AAHRMAOAMEN1 | |
| SCHEMBL11695787 | 0.76 | TRPV1 (0.40) | MAOA | |
| SCHEMBL29394156 | 0.75 | PNMT (0.53) | MAOAALDH1A1MAPTTSHRCES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | claimed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | claimed |
| US-6369246-B2 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS | DR. KEITH CHAN, GLOBOASIA, LLC | 2002-04-09 | — | — | US | claimed |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | CHAN, KEITH | 2001-08-30 | — | — | US | claimed |
| WO-2000061536-A2 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA, L.L.C. (US) | 2000-10-19 | — | — | WO | claimed |
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | disclosed |
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | disclosed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | disclosed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | disclosed |
| US-6369246-B2 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS, ANTITUMOR AGENTS | DR. KEITH CHAN, GLOBOASIA, LLC | 2002-04-09 | — | — | US | disclosed |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | CHAN, KEITH | 2001-08-30 | — | — | US | disclosed |
| WO-2000061536-A2 | SYNTHESIS AND PHARMACEUTICALS OF NOVEL 9-SUBSTITUTED-1,5-DICHLOROANTHRACENE ANALOGS | GLOBOASIA, L.L.C. (US) | 2000-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | GPX4, GPX1, AGK | NSD2 3492/4885ADORA2A 1702/4885AHR 3115/4885 |
| US-20010018539-A1 | Synthesis and pharmaceuticals of novel 9-substituted-1, 5-dichloroanthracene analogs | C3AR1, C5AR2, TLR2 | NSD2 3252/4885ADORA2A 984/4885AHR 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.