Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | HPN | P05981 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | KDR | P35968 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6902816 | 0.86 | MAOA (0.61) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL29522447 | 0.86 | MAOA (0.61) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL11041196 | 0.83 | CYP2A6 (0.44) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL20589092 | 0.82 | AHR (0.47) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL7029795 | 0.81 | NSD2 (0.40) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL6906371 | 0.80 | METAP1 (0.54) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL11661126 | 0.79 | L3MBTL1 (0.39) | TSHRMEN1USP2ALDH1A1HPN | |
| Anthracene SCHEMBL28843478 | 0.79 | MAOA (0.52) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL8947485 | 0.76 | CES1 (0.38) | TSHRMEN1USP2ALDH1A1HPN | |
| SCHEMBL3787825 | 0.76 | MAOA (0.46) | TSHRMEN1USP2ALDH1A1HPN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6596774-B1 | For their ability to inhibit the growth of human oral epidermoid carcinoma cells, human cervical carcinoma cells and Chinese hamster ovary cells | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-22 | — | — | US | disclosed |
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | NATIONAL SCIENCE COUNCIL OF R.O.C. (TW) | 2003-07-17 | — | — | US | disclosed |
| US-6372785-B1 | DRUGS FOR ANTIALLERGENS AND ANTIINFLAMMATORY AGENTS | KEITH CHAN, PRESIDENT GLOBOASIA, LLC | 2002-04-16 | — | — | US | disclosed |
| US-5434264-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-07-18 | — | — | US | disclosed |
| US-5300642-A | α, α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-04-05 | — | — | US | disclosed |
| EP-0311010-B1 | Alpha,Alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | DU PONT MERCK PHARMA (US) | 1994-02-02 | — | — | EP | disclosed |
| EP-0532054-A1 | Process for preparing alpha,alpha-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-03-17 | — | — | EP | disclosed |
| US-5173489-A | α,α-disubstituted aromatics and heteroaromatics as cognition enhancers | THE DUPONT MERCK PHARMACEUTICAL CO. (US) | 1992-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135060-A1 | Synthesis, lipid peroxidation and cytotoxic evaluation of 10-substituted 1,5-dichloro-9(10H)-anthracenone derivatives | GPX4, GPX1, AGK | TSHR 2891/4885MEN1 1117/4885USP2 4578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.