Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 3/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.42 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPN | P05981 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28863723 | 0.86 | METAP1 (0.43) | METAP1HSP90AA1ITGA1GABRPGABRD | |
| SCHEMBL29522447 | 0.83 | MAOA (0.61) | MAOAMAOBMEN1USP2ALDH1A1 | |
| SCHEMBL6902816 | 0.83 | MAOA (0.61) | MAOAMAOBMEN1USP2ALDH1A1 | |
| SCHEMBL7103871 | 0.80 | TSHR (0.57) | MAOAMEN1USP2ALDH1A1HPN | |
| SCHEMBL10691369 | 0.80 | METAP1 (0.71) | METAP1MAOAMAOBHSP90AA1S100A4 | |
| SCHEMBL10694841 | 0.80 | MAOA (0.67) | METAP1MAOAHSP90AA1ITGA1S100A4 | |
| Anthracene SCHEMBL28843478 | 0.79 | MAOA (0.52) | MAOAMAOBMEN1USP2ALDH1A1 | |
| SCHEMBL11661126 | 0.79 | L3MBTL1 (0.39) | METAP1ITGA1MEN1USP2ALDH1A1 | |
| SCHEMBL11661562 | 0.77 | METAP1 (0.50) | METAP1MAOAMAOBHSP90AA1ITGA1 | |
| SCHEMBL8949640 | 0.76 | METAP1 (0.53) | METAP1MAOAMAOBHSP90AA1ITGA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |