Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | PNMT | P11086 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD1 | P21728 | 3/20 | 0.38 |
| ▸ | DRD5 | P21918 | 3/20 | 0.38 |
| ▸ | DRD4 | P21917 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4923859 | 0.93 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL1861381 | 0.85 | ADRA2A (0.48) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL29394156 | 0.77 | PNMT (0.53) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL9672282 | 0.77 | CYP1A2 (0.52) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL3284763 | 0.77 | PNMT (0.53) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL30253262 | 0.77 | CYP1A2 (0.52) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL29935665 | 0.76 | CYP1A2 (0.48) | TSHRLMNACYP1A2DRD2DRD1 | |
| Bromide SCHEMBL20542577 | 0.76 | PNMT (0.52) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL8468364 | 0.76 | MAOA (0.38) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D | |
| SCHEMBL19939674 | 0.74 | HSD17B3 (0.43) | ADRA2AADRA2BADRA2CCYP2D6ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6815481-B2 | FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-11-09 | — | — | US | disclosed |
| US-20020032256-A1 | Polybutadiene composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-03-14 | — | — | US | disclosed |