SCHEMBL6902878

SCHEMBL6902878

COc1ccc2c(c1Cl)C(=O)c1ccccc1C2=O

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 7/20 0.68
SMN1; SMN2 Q16637 5/20 0.68
NPC1 O15118 3/20 0.68
MAPT P10636 7/20 0.66
MEN1 O00255 5/20 0.66
KMT2A Q03164 5/20 0.66
ALDH1A1 P00352 5/20 0.65
KDM4E B2RXH2 3/20 0.65
TDP1 Q9NUW8 2/20 0.65
USP2 O75604 2/20 0.65
DUSP3 P51452 1/20 0.65
MAPK1 P28482 4/20 0.54
ADORA2A P29274 3/20 0.54
NPSR1 Q6W5P4 2/20 0.54
POLB P06746 2/20 0.54
FGB P02675 1/20 0.54
THRB P10828 1/20 0.54
PPARG P37231 1/20 0.54
NCOA2 Q15596 1/20 0.54
NCOA1 Q15788 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11107245 0.81 TTR (0.54) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL496978 0.81 RAB9A (1.00) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL11303111 0.80 ADORA2A (0.68) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL1426486 0.79 MAPT (1.00) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL9846590 0.79 RAB9A (0.68) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL9751849 0.79 RAB9A (0.68) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL31441205 0.79 MAPT (1.00) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL29929605 0.79 MAPT (1.00) RAB9ASMN1; SMN2NPC1MAPTMEN1
1,4-Dimethoxyanthraquinone SCHEMBL3417221 0.79 MAPT (1.00) RAB9ASMN1; SMN2NPC1MAPTMEN1
SCHEMBL8769865 0.79 MAPT (0.49) RAB9ASMN1; SMN2NPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed