Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.40 |
| ▸ | DNASE1 | P24855 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | CCND2 | P30279 | 1/20 | 0.35 |
| ▸ | CCND3 | P30281 | 1/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.35 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557799 | 0.80 | ALDH1A1 (0.51) | ALDH1A1HSD17B10TSHRKDM4EPIM1 | |
| SCHEMBL9443458 | 0.75 | HPGD (0.52) | ALDH1A1HSD17B10USP2KDM4EPIM1 | |
| SCHEMBL10514956 | 0.74 | HTR2C (0.48) | ALDH1A1HSD17B10KDM4EJAK2LMNA | |
| SCHEMBL6341275 | 0.71 | HCAR2 (0.35) | ALDH1A1HSD17B10KDM4EPIM1PIM3 | |
| SCHEMBL30504558 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HSD17B10USP2TSHRKDM4E | |
| SCHEMBL3475236 | 0.71 | ALDH1A1 (0.44) | ALDH1A1HSD17B10USP2TSHRKDM4E | |
| SCHEMBL28281274 | 0.70 | PIM1 (0.44) | ERCC1DNASE1FEN1ERCC4ALDH1A1 | |
| SCHEMBL27541984 | 0.70 | HPGD (0.47) | ALDH1A1HSD17B10USP2KDM4EHPGD | |
| SCHEMBL6898646 | 0.70 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRKDM4EPIM1 | |
| SCHEMBL10698893 | 0.69 | KDM4E (0.47) | ALDH1A1HSD17B10USP2TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-A4 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401829-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | Microbiotix, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102792-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2002-12-27 | — | — | WO | disclosed |