Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | GSK3A | P49840 | 2/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.42 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7557799 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDHSD17B10PRKD3 | |
| SCHEMBL6904347 | 0.81 | KDM4E (0.41) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL6341275 | 0.78 | HCAR2 (0.35) | ALDH1A1KDM4EHPGDHSD17B10PRKD3 | |
| SCHEMBL6904417 | 0.74 | IDO1 (0.38) | ALDH1A1KDM4EKCNH2TDP1CYP1A2 | |
| SCHEMBL9523923 | 0.74 | LMNA (0.59) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL5569300 | 0.74 | KDM4E (0.50) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL6897930 | 0.73 | KDM4E (0.49) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL9234797 | 0.72 | PRKD3 (0.46) | ALDH1A1KDM4EHPGDHSD17B10PMP22 | |
| SCHEMBL11205213 | 0.71 | PIM1 (0.42) | ALDH1A1KDM4EHPGDHSD17B10PRKD3 | |
| SCHEMBL6773934 | 0.71 | KDM4E (0.76) | ALDH1A1KDM4EHPGDHSD17B10PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-A4 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401829-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | Microbiotix, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102792-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2002-12-27 | — | — | WO | disclosed |