Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | TOP2A | P11388 | 2/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6898646 | 0.87 | ALDH1A1 (0.44) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL6341275 | 0.82 | HCAR2 (0.35) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL3474228 | 0.80 | ALDH1A1 (0.53) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL6903129 | 0.80 | ERCC1 (0.40) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL6904417 | 0.78 | IDO1 (0.38) | ALDH1A1KDM4ECYP2C9CYP1A2 | |
| SCHEMBL3341252 | 0.76 | KDM4E (0.58) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| Cyclopropane SCHEMBL3447310 | 0.74 | ALDH1A1 (0.56) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL30866391 | 0.73 | KDM4E (0.63) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL6703755 | 0.72 | KDM4E (0.62) | ALDH1A1LMNAKDM4EHPGDHSD17B10 | |
| SCHEMBL11204668 | 0.72 | PIM1 (0.40) | ALDH1A1LMNAKDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020169168-A1 | Pharmaceutical formulations of ciprofloxacin | STREUFF BERND (DE) | 2002-11-14 | — | — | US | disclosed |