Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | MDM4 | O15151 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PTGIR | P43119 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7619248 | 1.00 | LMNA (0.42) | LMNAMDM4MDM2NPC1RAB9A | |
| SCHEMBL3455025 | 0.93 | MDM4 (0.39) | MDM4MDM2NPC1RAB9APTGIR | |
| SCHEMBL3455372 | 0.92 | CNR2 (0.38) | LMNAMDM4MDM2NPC1RAB9A | |
| SCHEMBL635894 | 0.91 | RORC (0.43) | LMNAMDM4MDM2NPC1RAB9A | |
| SCHEMBL635895 | 0.91 | RORC (0.43) | LMNAMDM4MDM2NPC1RAB9A | |
| SCHEMBL30519772 | 0.86 | MEN1 (0.51) | MDM4MDM2NPC1RAB9APTGIR | |
| SCHEMBL55267 | 0.86 | MEN1 (0.51) | MDM4MDM2NPC1RAB9APTGIR | |
| SCHEMBL29435442 | 0.86 | MEN1 (0.51) | MDM4MDM2NPC1RAB9APTGIR | |
| SCHEMBL635027 | 0.86 | MEN1 (0.51) | MDM4MDM2NPC1RAB9APTGIR | |
| SCHEMBL8827406 | 0.86 | MEN1 (0.51) | MDM4MDM2NPC1RAB9APTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423009-A2 | HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES | Bayer CropScience AG (DE) | 2004-06-02 | — | — | EP | disclosed |
| WO-2003017766-A2 | HERBICIDES MADE FROM SUBSTITUTED ARYL KETONES | BAYER CROPSCIENCE AG (DE) | 2003-03-06 | — | — | WO | disclosed |
| WO-2003000058-A1 | SELECTIVE HERBICIDES BASED ON PYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2003-01-03 | — | — | WO | disclosed |