SCHEMBL635895

SCHEMBL635895

CCOC(=O)C(C)N(C(=O)c1ccccc1)c1ccc(F)c(Cl)c1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORC P51449 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
PLA2G1B P04054 1/20 0.41
HTT P42858 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
ATG4B Q9Y4P1 1/20 0.41
MDM4 O15151 2/20 0.41
MDM2 Q00987 2/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 1/20 0.40
PTGIR P43119 1/20 0.40
LMNA P02545 2/20 0.39
USP2 O75604 1/20 0.39
TSPO P30536 1/20 0.38
PTPRC P08575 1/20 0.38
PTPN2 P17706 1/20 0.38
PTPN1 P18031 1/20 0.38
PTPA Q15257 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL635894 1.00 RORC (0.43) RORCMEN1KMT2AALDH1A1PLA2G1B
SCHEMBL11284170 0.93 MEN1 (0.46) RORCMEN1KMT2AALDH1A1PLA2G1B
SCHEMBL6903150 0.91 LMNA (0.42) MEN1KMT2AALDH1A1PLA2G1BHTT
SCHEMBL7619248 0.91 LMNA (0.42) MEN1KMT2AALDH1A1PLA2G1BHTT
SCHEMBL8827400 0.89 RORC (0.45) RORCMEN1KMT2AALDH1A1PLA2G1B
SCHEMBL6294014 0.89 RORC (0.45) RORCMEN1KMT2AALDH1A1PLA2G1B
SCHEMBL163055 0.89 RORC (0.45) RORCMEN1KMT2AALDH1A1PLA2G1B
SCHEMBL3455025 0.89 MDM4 (0.39) MEN1KMT2AALDH1A1PLA2G1BHTT
SCHEMBL10858376 0.88 MEN1 (0.42) RORCMEN1KMT2AALDH1A1PLA2G1B
SCHEMBL30519772 0.88 MEN1 (0.51) MEN1KMT2APLA2G1BHTTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 US claimed
EP-0407341-B1 Selective herbicidal agent CIBA GEIGY AG (CH) 1995-12-06 EP claimed
US-5059239-A Preemergence; postemergence; grains CIBA-GEIGY CORPORATION (US) 1991-10-22 US claimed
EP-1727906-B1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF PLANT SCIENCE GMBH (DE) 2012-02-22 EP disclosed
CN-100585938-C Nonaqueous electrolyte battery, battery pack and automobile TOSHIBA KK 2010-01-27 CN disclosed
US-20090300800-A1 D-Amino Acid a Selectable Marker for Barley (Hordeum Vulgare L.) Transformation BASF PLANT SCIENCE GMBH (DE) 2009-12-03 US disclosed
US-20090106856-A1 Selection System for Wheat BASF PLANT SCIENCE GMBH (DE) 2009-04-23 US disclosed
US-20090083883-A1 D-Amino Acid Selection For Soybean BASF PLANT SCIENCE GMBH (DE) 2009-03-26 US disclosed
US-20090038025-A1 Selection system for maize transformation BASF PLANT SCIENCE GMBH (DE) 2009-02-05 US disclosed
CN-101351555-A A new selection system for wheat BASF PLANT SCIENCE GMBH (DE) 2009-01-21 CN disclosed
EP-1996712-A2 D-AMINO ACID SELECTION FOR SOYBEAN BASF Plant Science GmbH (DE) 2008-12-03 EP disclosed
WO-2005090581-A1 IMPROVED CONSTRUCTS FOR MARKER EXCISION BASED ON DUAL-FUNCTION SELECTION MARKER BASF PLANT SCIENCE GMBH (DE) 2005-09-29 WO disclosed
EP-0671434-A1 Blends based on fluorosilicone elastomers and vinylidene fluoride polymers DOW CORNING CORPORATION (US) 1995-09-13 EP disclosed
EP-0230475-B1 NOVEL UREA DERIVATIVES, PROCESSES FOR PRODUCTION THEREOF AND HERBICIDE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1992-03-18 EP disclosed
US-5059239-A Preemergence; postemergence; grains CIBA-GEIGY CORPORATION (US) 1991-10-22 US disclosed
EP-0184385-B1 N-[(4,6-Dimethoxypyrimidin-2-YL)Aminocarbonyl]-3-trifluoromethylpyridine-2-sulfonamide or salts thereof, herbicidal composition containing the same, and processs for the production of the compound ISHIHARA SANGYO KAISHA LTD. (JP) 1990-09-26 EP disclosed
US-4838924-A NONPHYTOTOXIC MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-06-13 US disclosed
US-4744814-A NONPHYTOTOXIC FOR TOMATOS AND TURF ISHIHARA SANGYO KAISHA (JP) 1988-05-17 US disclosed
US-4399072-A HERBICIDE, FUNGICIDE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-08-16 US disclosed
US-4280835-A Herbicidal N-phenyl-N-methylurea derivatives SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1981-07-28 US disclosed