Hydrochloric Acid

Hydrochloric Acid

SCHEMBL6903687

CCC1=Cc2c(-c3cccc4ccccc34)cccc2C1[Zr+2](C1C(CC)=Cc2c(-c3cccc4ccccc34)cccc21)=[Si](C)C.[Cl-].[Cl-]

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC6A2 known ✓ P23975 1/20 0.31
SLC6A3 known ✓ Q01959 1/20 0.31
SLC6A4 P31645 5/20 0.32
DRD2 P14416 1/20 0.32
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
HTR7 P34969 1/20 0.30
KDM1A O60341 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL31126400 1.00 SLC6A4 (0.32) SLC6A4DRD2SLC6A2SLC6A3KDM4E
Hydrochloric Acid SCHEMBL4659381 0.91 SLC6A4 (0.33) SLC6A4DRD2HTR7
Hydrochloric Acid SCHEMBL4658320 0.90 ALDH1A1 (0.32) ALDH1A1HPGD
Hydrochloric Acid SCHEMBL4658198 0.89 CNR1 (0.34) SLC6A4DRD2HTR7
Hydrochloric Acid SCHEMBL4659084 0.89 SLC6A4 (0.30) SLC6A4DRD2
Hydrochloric Acid SCHEMBL4659142 0.88 CNR1 (0.38) SLC6A4DRD2SLC6A2MAPT
Hydrochloric Acid SCHEMBL4659102 0.87 NPC1 (0.30) MAPT
Hydrochloric Acid SCHEMBL4660372 0.87
Hydrochloric Acid SCHEMBL5722650 0.87 DRD2 (0.30) SLC6A4DRD2
Hydrochloric Acid SCHEMBL4659079 0.87 HTR1A (0.32) HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0783022-B2 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2016-01-20 EP disclosed
EP-1088836-B1 ETHYLENE/ALPHA-OLEFIN/UNCONJUGATED POLYENE COPOLYMER RUBBER, RUBBER COMPOSITION FOR SEALING, MOLDED RUBBER FOR SEALING, AND PROCESS FOR PRODUCING THE MOLDED RUBBER PART MITSUI CHEMICALS INC (JP) 2012-11-21 EP disclosed
EP-0783022-B1 ETHYLENIC POLYMER COMPOSITION MITSUI CHEMICALS INC (JP) 2004-09-22 EP disclosed
US-6677411-B2 AS CATALYST SUPPORT AN ION-EXCHANGE LAYERED SILICATE HAVING A SPECIFIC PORE SIZE DISTRIBUTION CURVE JAPAN POLYCHEM CORPORATION (JP) 2004-01-13 US disclosed
US-6635727-B1 Random copolymer comprising structural units derived from comonomers of ethylene, one or more alpha-olefins, one or more trienes, and one or more non-conjugated polyenes in specified amounts and having specified intrinsic viscosity MITSUI CHEMICALS, INC. (JP) 2003-10-21 US disclosed
US-6635705-B2 Crosslinked crystalline polyolefin resin, an ethylene-alpha-olefin-non-conjugated polyene copolymer rubber, and polyisobutylene, butyl rubber or a propylene-ethylene copolymer MITSUI CHEMICALS, INC. (JP) 2003-10-21 US disclosed
US-20030027950-A1 Component of catalyst for olefin polymerization JAPAN POLYCHEM CORPORATION (JP) 2003-02-06 US disclosed
US-6410650-B1 MOLDING MATERIALS MITSUI CHEMICALS INC (JP) 2002-06-25 US disclosed
US-20020055591-A1 Olefinic thermoplastic elastomer composition and method for producing the same MITSUI CHEMICALS, INC. 2002-05-09 US disclosed
EP-1152016-A1 ETHYLENE COPOLYMER RUBBER, PROCESS FOR PRODUCING THE SAME, AND USE Mitsui Chemicals, Inc. (JP) 2001-11-07 EP disclosed
EP-1088836-A1 ETHYLENE/ALPHA-OLEFIN/UNCONJUGATED POLYENE COPOLYMER RUBBER, RUBBER COMPOSITION FOR SEALING, MOLDED RUBBER FOR SEALING, AND PROCESS FOR PRODUCING THE MOLDED RUBBER Mitsui Chemicals, Inc. (JP) 2001-04-04 EP disclosed
EP-1065241-A2 Olefinic thermoplastic elastomer composition and method for producing the same Mitsui Chemicals, Inc. (JP) 2001-01-03 EP disclosed
US-6063871-A SPECIFIC HIGH-DENSITY ETHYLENE POLYMER AND A SPECIFIC ETHYLENE POLYMER, IN WHICH AT LEAST ONE IS PREPARED USING A METALLOCENE CATALYST, AND THE DENSITY RATIO THEREBETWEEN EXCEEDS 1; MOLDABILITY, CRACK RESISTANCE, STRENGTH AND RIGIDITY MITSUI PETROCHEMICAL INDUSTRIES, INC. (JP) 2000-05-16 US disclosed
EP-0783022-A1 ETHYLENIC POLYMER COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1997-07-09 EP disclosed