Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.43 |
| ▸ | METAP1 | P53582 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6903273 | 0.96 | KDM4E (0.51) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL27725861 | 0.85 | KDM4E (0.50) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL27651327 | 0.84 | KDM4E (0.49) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL6899249 | 0.81 | KDM4E (0.45) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL29452704 | 0.80 | KDM4E (0.57) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL168649 | 0.80 | KDM4E (0.57) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL1838784 | 0.77 | KDM4E (0.54) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL17487291 | 0.77 | ALDH1A1 (0.53) | KDM4EGAACYP3A4NPC1RAB9A | |
| SCHEMBL30050527 | 0.77 | KDM4E (0.59) | KDM4EPKMGAAALOX12TDP1 | |
| SCHEMBL167490 | 0.77 | KDM4E (0.59) | KDM4EPKMGAAALOX12TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6743754-B2 | A SULFONYLUREA AND ONE OR MORE SURFACTANTS COMPRISING AS STRUCTURAL ELEMENT AT LEAST 10 ALKYLENE OXIDE UNITS. | AVENTIS CROPSCIENCE GMBH (DE) | 2004-06-01 | — | — | US | disclosed |
| US-6693063-B2 | HALOGENATED HYDROXYBENZONITRILE DERIVATIVE WITH SPECIFIC SURFACTANTS | AVENTIS CROPSCIENCE GMBH (DE) | 2004-02-17 | — | — | US | disclosed |
| US-6569805-B1 | Synergistic mixture of certain phenylsulfonylureas and/or their salts and vegetable oils for controlling weeds in crops | AVENTIS CROPSCIENCE GMBH (DE) | 2003-05-27 | — | — | US | disclosed |
| US-20020115569-A1 | Herbicidal composition | AVENTIS CROPSCIENCE GMBH (DE) | 2002-08-22 | — | — | US | disclosed |
| US-20020091066-A1 | Herbicidal compositions | BAYER CROPSCIENCE GMBH (DE) | 2002-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091066-A1 | Herbicidal compositions | CBR1, CBR3, GLRA1 | KDM4E 3026/4885PKM 4319/4885GAA 1644/4885 |
| US-20020115569-A1 | Herbicidal composition | CBR1, DDT, CYP1A1 | KDM4E 3552/4885PKM 4145/4885GAA 1164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.