Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | PTGES | O14684 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15502437 | 0.81 | KCNH2 (0.46) | KDM4EALDH1A1ALOX15HPGDTSHR | |
| SCHEMBL7113113 | 0.77 | ALDH1A1 (0.45) | KDM4ERXFP1ALDH1A1HSD17B10MAPT | |
| SCHEMBL5856135 | 0.77 | KMT2A (0.61) | KDM4EALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL11429696 | 0.75 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTKMT2AALOX5 | |
| SCHEMBL11022178 | 0.72 | NPC1 (0.43) | KDM4ERXFP1ALDH1A1HPGDMAPT | |
| SCHEMBL13108224 | 0.70 | ADORA3 (0.44) | KDM4EALDH1A1ALOX15HPGDTSHR | |
| SCHEMBL13107611 | 0.69 | KDM4E (0.47) | KDM4ERXFP1ALDH1A1ALOX15HPGD | |
| SCHEMBL10974102 | 0.68 | NPC1 (0.43) | KDM4ERXFP1ALDH1A1ALOX15HPGD | |
| SCHEMBL860929 | 0.68 | KEAP1 (0.57) | KDM4EALDH1A1ALOX15HPGDTSHR | |
| SCHEMBL25941697 | 0.68 | MAPT (0.53) | ALDH1A1ALOX15HPGDHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401829-A4 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX INC (US) | 2004-10-27 | — | — | EP | disclosed |
| EP-1401829-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | Microbiotix, Inc. (US) | 2004-03-31 | — | — | EP | disclosed |
| WO-2002102792-A1 | NOVEL HETEROCYCLIC ANTIBACTERIAL COMPOUNDS | MICROBIOTIX, INC. (US) | 2002-12-27 | — | — | WO | disclosed |