Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554403 | 0.74 | ALDH1A1 (0.60) | ALDH1A1KDM4EATMLMNASMN1; SMN2 | |
| SCHEMBL392370 | 0.72 | LMNA (0.55) | ALDH1A1KDM4EATMLMNASMN1; SMN2 | |
| Propachlor SCHEMBL65571 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNASMN1; SMN2TP53 | |
| Propachlor SCHEMBL1701162 | 0.72 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL4679419 | 0.70 | HPGD (0.69) | ALDH1A1KDM4EATMLMNASMN1; SMN2 | |
| SCHEMBL4682930 | 0.70 | LMNA (0.64) | ALDH1A1KDM4EATMLMNASMN1; SMN2 | |
| SCHEMBL6626711 | 0.70 | LMNA (0.51) | ALDH1A1KDM4EATMLMNASMN1; SMN2 | |
| SCHEMBL9869949 | 0.69 | ALDH1A1 (0.75) | ALDH1A1KDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL22387594 | 0.69 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNASMN1; SMN2TP53 | |
| SCHEMBL9869948 | 0.69 | ALDH1A1 (0.75) | ALDH1A1KDM4ELMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | BAYER CROPSCIENCE AG (DE) | 2004-12-09 | — | — | US | disclosed |
| EP-1265852-A1 | SUBSTITUTED IMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2002-12-18 | — | — | EP | disclosed |
| WO-2001056975-A1 | SUBSTITUTED IMIDE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-08-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040248958-A1 | Heterocyclic amide derivatives | DDT, CYP2E1, CYP1A1 | ALDH1A1 116/4885KDM4E 1089/4885ATM 3315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.