Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGL | P06737 | 18/20 | 0.71 |
| ▸ | PYGM | P11217 | 11/20 | 0.71 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14193363 | 0.85 | PYGL (0.64) | PYGLPYGMSMYD3 | |
| SCHEMBL4801410 | 0.83 | PYGL (1.00) | PYGLPYGMSMYD3 | |
| SCHEMBL17149871 | 0.81 | SMYD3 (0.67) | PYGLPYGMSMYD3 | |
| SCHEMBL3603066 | 0.78 | SMYD3 (0.69) | PYGLPYGMSMYD3 | |
| SCHEMBL3609215 | 0.78 | SMYD3 (0.69) | PYGLPYGMSMYD3 | |
| SCHEMBL3603062 | 0.78 | SMYD3 (0.69) | PYGLPYGMSMYD3 | |
| SCHEMBL14193346 | 0.78 | SMYD3 (0.57) | PYGLPYGMSMYD3 | |
| SCHEMBL11888212 | 0.78 | SMYD3 (0.79) | PYGLPYGMSMYD3 | |
| SCHEMBL763943 | 0.77 | SMYD3 (0.77) | PYGLSMYD3 | |
| SCHEMBL4803861 | 0.76 | PYGL (1.00) | PYGLPYGM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040002495-A1 | Lactam glycogen phosphorylase inhibitors and method of use | BRISTOL-MYERS SQUIBB COMPANY | 2004-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040002495-A1 | Lactam glycogen phosphorylase inhibitors and method of use | PYGL, PYGM, GYS2 | PYGL 1/4885PYGM 2/4885SMYD3 2280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.