Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 11/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.55 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.55 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.52 |
| ▸ | EGFR | P00533 | 1/20 | 0.52 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.52 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6904789 | 1.00 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4DRECQL | |
| SCHEMBL1959906 | 0.90 | SMN1; SMN2 (0.62) | PDE4BRECQLSMN1; SMN2HIF1AEGFR | |
| SCHEMBL1959904 | 0.90 | SMN1; SMN2 (0.62) | PDE4BRECQLSMN1; SMN2HIF1AEGFR | |
| Hydrochloric Acid SCHEMBL1959669 | 0.89 | SMN1; SMN2 (0.60) | PDE4BRECQLSMN1; SMN2HIF1AEGFR | |
| Hydrochloric Acid SCHEMBL1959671 | 0.89 | SMN1; SMN2 (0.60) | PDE4BRECQLSMN1; SMN2HIF1AEGFR | |
| SCHEMBL1957258 | 0.83 | RECQL (0.55) | PDE4BRECQLSMN1; SMN2HIF1AEGFR | |
| SCHEMBL1957259 | 0.83 | RECQL (0.55) | PDE4BRECQLSMN1; SMN2HIF1AEGFR | |
| SCHEMBL5190968 | 0.80 | PDE4A (0.50) | PDE4APDE4BPDE4CPDE4DTUBB4A | |
| SCHEMBL4990088 | 0.80 | MEN1 (0.59) | PDE4APDE4BPDE4CPDE4DRECQL | |
| SCHEMBL4990101 | 0.80 | MEN1 (0.59) | PDE4APDE4BPDE4CPDE4DRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040019106-A1 | Novel immunotherapeutic agents | MULLER GEORGE W (US) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019106-A1 | Novel immunotherapeutic agents | NFKBIA, RELA, IKBKG | PDE4A 22/4885PDE4B 33/4885PDE4C 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.