Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.44 |
| ▸ | CES1 | P23141 | 2/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA7 | P43166 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5816889 | 0.85 | MMP8 (0.40) | MMP8TSHRMEN1KMT2ANPSR1 | |
| SCHEMBL7039390 | 0.80 | SMN1; SMN2 (0.46) | MMP8CA9MEN1KMT2AMAPT | |
| SCHEMBL25117945 | 0.79 | CYP3A4 (0.42) | MEN1KMT2ALMNAMAPTALDH1A1 | |
| SCHEMBL3385442 | 0.79 | ALDH1A1 (0.48) | KMT2ANPSR1LMNAMAPTALDH1A1 | |
| SCHEMBL5747385 | 0.78 | MMP8 (0.43) | MMP8MEN1KMT2ANPSR1LMNA | |
| SCHEMBL9366709 | 0.78 | MAPT (0.49) | CES2CES1MMP8TSHRMEN1 | |
| SCHEMBL5530167 | 0.77 | MMP8 (0.49) | CES2CES1MMP8TSHRMEN1 | |
| SCHEMBL13532053 | 0.76 | ALDH1A1 (0.36) | MMP8MEN1KMT2ALMNAMAPT | |
| SCHEMBL27631956 | 0.76 | MMP8 (0.44) | MMP8TSHRCA12CA1CA2 | |
| SCHEMBL6904784 | 0.75 | RORC (0.44) | MMP8TSHRCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1197841-C | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2005-04-20 | — | — | CN | disclosed |
| EP-1002788-B1 | Process for preparing halogenated phenylmalonates | BASF AG (DE) | 2004-03-10 | — | — | EP | disclosed |
| EP-1002788-A1 | Process for preparing halogenated phenylmalonates | American Cyanamid Company (US) | 2000-05-24 | — | — | EP | disclosed |
| CN-1250044-A | Process for producing halogenated phenyl malonic ester | AMERICAN CYANAMID CO (US) | 2000-04-12 | — | — | CN | disclosed |