Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.49 |
| ▸ | LIPE | Q05469 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181473 | 0.88 | HPGD (0.61) | TBXAS1ALDH1A1HPGDCYP4Z1LIPE | |
| SCHEMBL7969106 | 0.87 | TBXAS1 (0.57) | TBXAS1ALDH1A1HPGDCYP4Z1GAA | |
| SCHEMBL3581393 | 0.86 | TBXAS1 (0.56) | TBXAS1SMN1; SMN2LTA4H | |
| SCHEMBL25242319 | 0.85 | TBXAS1 (0.54) | TBXAS1ALDH1A1HPGDCYP4Z1LIPE | |
| SCHEMBL27855918 | 0.84 | TBXAS1 (0.55) | TBXAS1SMN1; SMN2LTA4H | |
| SCHEMBL68851 | 0.84 | CYP4Z1 (0.62) | TBXAS1ALDH1A1CYP4Z1LIPEMAPT | |
| SCHEMBL7484161 | 0.83 | SMN1; SMN2 (0.62) | TBXAS1ALDH1A1LMNASMN1; SMN2LTA4H | |
| SCHEMBL3801206 | 0.83 | TBXAS1 (0.60) | TBXAS1ALDH1A1HPGDMAPTGAA | |
| SCHEMBL27855929 | 0.83 | TBXAS1 (0.54) | TBXAS1GAASMN1; SMN2LTA4H | |
| SCHEMBL6288240 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LIPEGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6806267-B1 | ANTITUMOUR AGENTS; OVERCOMING CHRONIC MYELOID LEUKEMIA ASSOCIATED DRUG RESISTANCE; SUCH AS 4-ACETOXY-5-PHENYL-NAPHTO(2,3-B)PYRROLO(1,2-D)(1,4)OXAZEPINE | THE UNIVERSITA'DI SIENA (IT) | 2004-10-19 | — | — | US | disclosed |
| EP-1255758-A1 | APOPTOSIS-INDUCING COMPOUNDS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2002-11-13 | — | — | EP | disclosed |
| WO-2001058904-A9 | APOPTOSIS-INDUCING COMPOUNDS | TRINITY COLLEGE DUBLIN (IE) | 2002-02-21 | — | — | WO | disclosed |
| WO-2001058904-A1 | APOPTOSIS-INDUCING COMPOUNDS | THE PROVOST, FELLOWS AND SCHOLARS OF THE COLLEGE OF THE HOLY AND UNDIVIDED TRINITY OF QUEEN ELIZABETH NEAR DUBLIN (IE) | 2001-08-16 | — | — | WO | disclosed |