Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | PDE4A | P27815 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7484161 | 0.93 | SMN1; SMN2 (0.62) | TBXAS1LMNAKDM4ECYP1A2CYP2D6 | |
| SCHEMBL11002749 | 0.93 | LMNA (0.58) | TBXAS1LMNAL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL9476115 | 0.89 | PLA2G4B (0.62) | TBXAS1LMNAKDM4ECYP1A2CYP2D6 | |
| SCHEMBL9140317 | 0.89 | PLA2G4B (0.62) | TBXAS1LMNAKDM4ECYP1A2CYP2D6 | |
| SCHEMBL181473 | 0.88 | HPGD (0.61) | TBXAS1SMN1; SMN2MAPTNPSR1ALDH1A1 | |
| SCHEMBL6781796 | 0.87 | TBXAS1 (0.57) | TBXAS1KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL8147343 | 0.87 | TBXAS1 (0.57) | TBXAS1KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL9787773 | 0.87 | TBXAS1 (0.57) | TBXAS1KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL10726761 | 0.87 | LTA4H (0.57) | TBXAS1KDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL7969106 | 0.87 | TBXAS1 (0.57) | TBXAS1KDM4ECYP1A2CYP2D6PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8921591-B2 | Process for synthesizing phenylacetic acid by carbonylation of toluene | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2014-12-30 | — | — | US | disclosed |
| US-20130303798-A1 | PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE | LANZHOU INSTITUTE OF CHEMICAL PHYSICS, CHINESE ACADEMY OF SCIENCES (CN) | 2013-11-14 | — | — | US | disclosed |
| US-7781592-B2 | Thione derivative, method for the preparation thereof, and pharmaceutical composition containing the same | CJ CHEILJEDANG CORPORATION (KR) | 2010-08-24 | — | — | US | disclosed |
| US-20080090875-A1 | Thione Derivative, Method For The Preparation Thereof, And Pharmaceutical Composition Containing The Same | CJC CORPORATION (KR) | 2008-04-17 | — | — | US | disclosed |
| WO-2005051941-A1 | THIONE DERIVATIVES, PROCESSES FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | CJ CORPORATION (KR) | 2005-06-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080090875-A1 | Thione Derivative, Method For The Preparation Thereof, And Pharmaceutical Composition Containing The Same | TPMT, TST, CYP3A5 | TBXAS1 276/4885LMNA 4506/4885L3MBTL1 3454/4885 |
| US-20130303798-A1 | PROCESS FOR SYNTHESIZING PHENYLACETIC ACID BY CARBONYLATION OF TOLUENE | DDT, HPD, PAH | TBXAS1 1435/4885LMNA 4096/4885L3MBTL1 3633/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.