SCHEMBL6904970

SCHEMBL6904970

CO[SiH](OC)C(CCSSSSCCC(c1ccccc1)[SiH](OC)OC)c1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.31
HRH1 P35367 2/20 0.31
MAPT P10636 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30
TSHR P16473 1/20 0.30
SLC6A4 P31645 1/20 0.30
CYP2C19 P33261 1/20 0.30
SLC6A3 Q01959 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9157825 0.89 SIGMAR1 (0.32) HTR2AHRH1
SCHEMBL11599684 0.88 SIGMAR1 (0.31)
SCHEMBL704370 0.79 AOC3 (0.40) HTR2AHRH1KMT2A
SCHEMBL705765 0.78 LMNA (0.43) HTR2AHRH1KMT2A
SCHEMBL2244555 0.77 HRH1 (0.50) HTR2AHRH1CYP1A2CYP3A4CYP2D6
SCHEMBL3110907 0.76 SIGMAR1 (0.40) HTR2AMAPT
SCHEMBL8992722 0.76 KCNH2 (0.43) HTR2AHRH1CYP1A2CYP3A4CYP2D6
SCHEMBL19470844 0.76 POLB (0.40) HTR2AMAPT
SCHEMBL2242686 0.76 HTR2A (0.40) HTR2AHRH1CYP1A2CYP3A4CYP2D6
SCHEMBL19470821 0.75 HTR2A (0.41) HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN claimed
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN claimed
CN-114685860-B Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2024-05-14 CN disclosed
CN-117986694-A Precipitated silica pretreated with coupling agent and polyethylene glycol for rubber compositions 固特异轮胎和橡胶公司 2024-05-07 CN disclosed
CN-113292772-B Accelerators for vulcanization of rubbery polymers 固特异轮胎和橡胶公司 2023-07-21 CN disclosed
CN-113667194-B Pneumatic tire 固特异轮胎和橡胶公司 2023-05-12 CN disclosed
CN-115466443-A Pneumatic tire 固特异轮胎和橡胶公司 2022-12-13 CN disclosed
CN-114685860-A Pretreatment method of silicon dioxide 固特异轮胎和橡胶公司 2022-07-01 CN disclosed
CN-114621375-A Rubber with main chain and end group functionalization 固特异轮胎和橡胶公司 2022-06-14 CN disclosed
CN-114591518-A Process for preparing silica/cellulose mixtures 固特异轮胎和橡胶公司 2022-06-07 CN disclosed
CN-111499942-B Pneumatic tire 固特异轮胎和橡胶公司 2022-05-24 CN disclosed
CN-111499942-A Pneumatic tire 固特异轮胎和橡胶公司 2020-08-07 CN disclosed
CN-110894314-A Resin modified oil-extended rubber 固特异轮胎和橡胶公司 2020-03-20 CN disclosed
CN-110872408-A Pneumatic tire 固特异轮胎和橡胶公司 2020-03-10 CN disclosed
CN-108070118-A Pneumatic tire 固特异轮胎和橡胶公司 2018-05-25 CN disclosed
EP-1448400-A1 TYRE WITH LOW ROLLING RESISTANCE, TREAD BAND AND ELASTOMERIC COMPOSITION USED THEREIN PIRELLI PNEUMATICI Società per Azioni (IT) 2004-08-25 EP disclosed
EP-1339539-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI Società per Azioni (IT) 2003-09-03 EP disclosed
EP-0941872-B1 Rubber composition reinforced with silica and tire with tread thereof GOODYEAR TIRE & RUBBER (US) 2003-08-06 EP disclosed
WO-2003037655-A1 TYRE WITH LOW ROLLING RESISTANCE, TREAD BAND AND ELASTOMERIC COMPOSITION USED THEREIN PIRELLI PNEUMATICI S.P.A. (IT) 2003-05-08 WO disclosed
WO-2002045942-A1 PROCESS FOR MANUFACTURING, MOULDING AND CURING TYRES FOR VEHICLES WHEELS PIRELLI PNEUMATICI S.P.A (IT) 2002-06-13 WO disclosed