Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 1/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11576796 | 0.88 | MAPT (0.66) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL27874651 | 0.87 | KMT2A (0.51) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL7888502 | 0.87 | KMT2A (0.57) | KMT2ANPC1MAPTLMNAKDM4E | |
| SCHEMBL10426838 | 0.86 | NPC1 (0.77) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL28091564 | 0.86 | MAPT (0.58) | KMT2ANPC1MAPTLMNANPSR1 | |
| SCHEMBL29771971 | 0.85 | STS (0.70) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL1682193 | 0.85 | STS (0.70) | KMT2ANPC1RAB9AMAPTLMNA | |
| SCHEMBL30033997 | 0.85 | RAB9A (0.67) | KMT2ARAB9AMAPTLMNAHCRTR1 | |
| SCHEMBL720460 | 0.85 | RAB9A (0.67) | KMT2ARAB9AMAPTLMNAHCRTR1 | |
| SCHEMBL30603177 | 0.85 | KMT2A (0.56) | KMT2ANPC1MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040019106-A1 | Novel immunotherapeutic agents | MULLER GEORGE W (US) | 2004-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040019106-A1 | Novel immunotherapeutic agents | NFKBIA, RELA, IKBKG | KMT2A 1693/4885NPC1 4804/4885RAB9A 4291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.