Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 6/20 | 0.62 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.62 |
| ▸ | RARB | P10826 | 4/20 | 0.62 |
| ▸ | RARG | P13631 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.53 |
| ▸ | BLVRB | P30043 | 1/20 | 0.53 |
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905676 | 1.00 | RARA (0.62) | RARACYP26A1RARBRARGKMT2A | |
| SCHEMBL501853 | 0.82 | CYP26B1 (0.57) | RARACYP26A1RARBRARGCYP3A4 | |
| SCHEMBL501852 | 0.82 | CYP26B1 (0.57) | RARACYP26A1RARBRARGCYP3A4 | |
| SCHEMBL13259701 | 0.81 | RARA (0.74) | RARACYP26A1RARBRARGKMT2A | |
| SCHEMBL6929375 | 0.80 | IGF1R (0.64) | KMT2ACYP3A4MEN1PIM1HDAC4 | |
| SCHEMBL6929376 | 0.80 | IGF1R (0.64) | KMT2ACYP3A4MEN1PIM1HDAC4 | |
| SCHEMBL8459704 | 0.77 | RARA (0.80) | RARACYP26A1RARBRARGKMT2A | |
| SCHEMBL9446527 | 0.77 | CYP26A1 (0.80) | RARACYP26A1RARBRARGKMT2A | |
| SCHEMBL29355626 | 0.77 | RARB (1.00) | RARACYP26A1RARBRARGKMT2A | |
| SCHEMBL726740 | 0.77 | RARB (1.00) | RARACYP26A1RARBRARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045611-A1 | USE OF A THIAZOLIDINEDIONE FOR THE REDUCTION OF SIDE EFFECTS OF CHEMOTHERAPY | N-GENE RESEARCH LABORATORIES INC. (US) | 2004-06-03 | — | — | WO | disclosed |