Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP26B1 | Q9NR63 | 1/20 | 0.57 |
| ▸ | PIM1 | P11309 | 5/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 4/20 | 0.52 |
| ▸ | GSK3B | P49841 | 2/20 | 0.46 |
| ▸ | RXRA | P19793 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RARA | P10276 | 4/20 | 0.43 |
| ▸ | RARB | P10826 | 4/20 | 0.43 |
| ▸ | RARG | P13631 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL501852 | 1.00 | CYP26B1 (0.57) | CYP26B1PIM1PIM2GSK3BRXRA | |
| SCHEMBL6905677 | 0.82 | RARA (0.62) | CYP26B1PIM1RXRARARARARB | |
| SCHEMBL6905676 | 0.82 | RARA (0.62) | CYP26B1PIM1RXRARARARARB | |
| SCHEMBL5084734 | 0.78 | CYP26B1 (0.75) | CYP26B1RXRARAB9ANPC1RARA | |
| SCHEMBL14425232 | 0.76 | CYP26B1 (0.65) | CYP26B1RXRARAB9ANPC1RARA | |
| SCHEMBL501585 | 0.75 | RXRA (0.56) | PIM1PIM2GSK3BRXRARAB9A | |
| SCHEMBL501583 | 0.75 | RXRA (0.56) | PIM1PIM2GSK3BRXRARAB9A | |
| SCHEMBL501582 | 0.75 | RXRA (0.56) | PIM1PIM2GSK3BRXRARAB9A | |
| SCHEMBL1619225 | 0.73 | RXRA (0.53) | PIM1PIM2GSK3BRXRARAB9A | |
| SCHEMBL22838105 | 0.73 | CYP26B1 (1.00) | CYP26B1RXRARARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291492-A1 | METHOD FOR FORMING ORGAN | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-11-26 | — | — | US | claimed |
| US-20070161105-A1 | Method of forming organ | REASEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-07-12 | — | — | US | claimed |
| EP-1612264-A1 | ORGAN-FORMING METHOD | Research Foundation Itsuu Laboratory (JP) | 2006-01-04 | — | — | EP | claimed |
| US-8105833-B2 | Method for forming organ | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2012-01-31 | — | — | US | disclosed |
| US-20090291492-A1 | METHOD FOR FORMING ORGAN | RESEARCH FOUNDATION ITSUU LABORATORY (JP) | 2009-11-26 | — | — | US | disclosed |
| US-20070161105-A1 | Method of forming organ | REASEARCH FOUNDATION ITSUU LABORATORY (JP) | 2007-07-12 | — | — | US | disclosed |
| EP-1612264-A1 | ORGAN-FORMING METHOD | Research Foundation Itsuu Laboratory (JP) | 2006-01-04 | — | — | EP | disclosed |