SCHEMBL29355626

SCHEMBL29355626

CC1(C)CCC(C)(C)c2cc(C(=O)Nc3ccc(C(=O)O)cc3)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 10/20 1.00
RARA P10276 9/20 1.00
RARG P13631 9/20 1.00
CYP26A1 O43174 6/20 1.00
CYP3A4 P08684 4/20 1.00
MEN1 O00255 2/20 1.00
KMT2A Q03164 2/20 1.00
ALDH1A1 P00352 1/20 1.00
CYP1A2 P05177 1/20 1.00
CYP2C9 P11712 1/20 1.00
TSHR P16473 1/20 1.00
MAPK1 P28482 1/20 1.00
CYP2C19 P33261 1/20 1.00
PGR P06401 1/20 0.84
ADORA3 P0DMS8 1/20 0.84
TBXA2R P21731 1/20 0.84
BLVRB P30043 1/20 0.84
CYP26B1 Q9NR63 2/20 0.74
RXRA P19793 9/20 0.67
RXRB P28702 8/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL726740 1.00 RARB (1.00) RARBRARARARGCYP26A1CYP3A4
Tamibarotene SCHEMBL36207 0.91 RARB (1.00) RARBRARARARGCYP26A1CYP3A4
Tamibarotene SCHEMBL29373818 0.91 RARB (1.00) RARBRARARARGCYP26A1CYP3A4
Tamibarotene SCHEMBL21055743 0.90 RARB (0.97) RARBRARARARGCYP26A1CYP3A4
SCHEMBL7621355 0.90 RARA (0.82) RARBRARARARGCYP26A1CYP3A4
SCHEMBL8459704 0.89 RARA (0.80) RARBRARARARGCYP26A1CYP3A4
SCHEMBL9446527 0.89 CYP26A1 (0.80) RARBRARARARGCYP26A1CYP3A4
SCHEMBL1616078 0.87 CYP26A1 (0.78) RARBRARARARGCYP26A1CYP3A4
SCHEMBL9446600 0.87 RARA (0.78) RARBRARARARGCYP26A1CYP3A4
SCHEMBL1616121 0.87 CYP26A1 (0.78) RARBRARARARGCYP26A1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1233 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES TRAILHEAD BIOSYSTEMS INC (US) 2026-05-07 US claimed
US-12599679-B2 Circular RNA compositions ORNA THERAPEUTICS, INC. (US) 2026-04-14 US claimed
US-12589189-B2 Use of retinoic acid receptor (RAR) agonists for reversing, preventing, or delaying calcification of aortic valve INSERM (INSTITUTE NATIONAL DE LA SANTA ET DE LA RECHERCHE MEDICALE) (FR) 2026-03-31 US claimed
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule HANGZHOU DAC BIOTECH CO., LTD (CN) 2026-03-17 US claimed
EP-4037672-B1 RETINOIC ACID RECEPTOR (RAR) AGONISTS FOR REVERSING, PREVENTING, OR DELAYING CALCIFICATION OF AORTIC VALVE INST NAT SANTE RECH MED (FR) 2026-03-11 EP claimed
US-12571044-B2 Classifier for identification of robust sepsis subtypes THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 2026-03-10 US claimed
EP-4008728-B1 CD70 BINDING MOLECULES AND METHODS OF USE THEREOF KITE PHARMA INC (US) 2025-12-17 EP claimed
US-20250339464-A1 ENDOGENOUS SIGNALING MOLECULE ACTIVATING CHIMERIC ANTIGEN RECEPTORS AND METHODS OF GENERATION THEREOF Miltenyi Biotec B.V. & Co. KG (DE) 2025-11-06 US claimed
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES HANGZHOU SEEHE BIOTECHNOLOGY CO., LTD (CN) 2025-11-06 US claimed
EP-4642492-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE FUNCTIONAL SMALL MOLECULE COMPOUNDS FOR ENHANCED TREATMENT OF REFRACTORY DISEASES Hangzhou Seehe Biotechnology Co., Ltd (CN) 2025-11-05 EP claimed
WO-2022132206-A1 SINGLE CELL SECRETOME ANALYSIS BECTON, DICKINSON AND COMPANY (US) 2022-06-23 WO claimed
WO-2022125439-A2 INNATE IMMUNE CELL SILENCING BY SIRP-ALPHA ENGAGER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-06-16 WO claimed
EP-4010082-A1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GammaDelta Therapeutics Limited (GB) 2022-06-15 EP claimed
US-20220178909-A1 MULTIPLEXED SINGLE CELL IMMUNOASSAY BECTON, DICKINSON AND COMPANY 2022-06-09 US claimed
EP-4008728-A1 CD70 BINDING MOLECULES AND METHODS OF USE THEREOF Kite Pharma, Inc. (US) 2022-06-08 EP claimed
EP-3986463-A1 A CONJUGATE OF A CYTOTOXIC AGENT TO A CELL BINDING MOLECULE WITH BRANCHED LINKERS Hangzhou Dac Biotech Co., Ltd. (CN) 2022-04-27 EP claimed
EP-3986476-A1 A FORMULATION OF A CONJUGATE OF A TUBULYSIN ANALOG TO A CELL-BINDING MOLECULE Hangzhou Dac Biotech Co., Ltd. (CN) 2022-04-27 EP claimed
WO-2022078524-A2 SPECIFIC CONJUGATION OF AN ANTIBODY HANGZHOU DAC BIOTECH CO., LTD. (CN) 2022-04-21 WO claimed
WO-2022034562-A1 MULTISPECIFIC ANTI-TCR DELTA VARIABLE 1 ANTIBODIES GammaDelta Therapeutics Limited (GB) 2022-02-17 WO claimed
CN-114040781-A Formulation of conjugate of TUBULYSIN derivative and cell binding molecule 杭州多禧生物科技有限公司 2022-02-11 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12599679-B2 Circular RNA compositions BCL6, BCL9, BCL6B RARB 2029/4885RARA 2505/4885RARG 2489/4885
US-20250339551-A1 AN ANTIBODY-DRUG CONJUGATE HAVING TWO OR MORE DIFFERENT FUNCTIONAL SMALL MOLECULES FOR ENHANCED TREATMENT OF REFRACTORY DISEASES FCGR2A, FCGR3B, FCGR1A RARB 2421/4885RARA 2105/4885RARG 1147/4885
US-12589189-B2 Use of retinoic acid receptor (RAR) agonists for reversing, preventing, or delaying calcification of aortic valve RARB, RARA, RXRB RARB 1/4885RARA 2/4885RARG 4/4885
US-12576124-B2 Formulation of a conjugate of a tubulysin analog to a cell-binding molecule CD4, TAP1, MCTS1 RARB 2779/4885RARA 3019/4885RARG 2579/4885
US-12571044-B2 Classifier for identification of robust sepsis subtypes LITAF, CD14, MYADM RARB 3477/4885RARA 4709/4885RARG 4573/4885
US-20260125650-A1 METHODS AND COMPOSITIONS FOR GENERATING HEPATOCYTES WNT3A, GSK3B, GSK3A RARB 70/4885RARA 354/4885RARG 134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.