Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEP1B | Q16820 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 2/20 | 0.46 |
| ▸ | NOS1 | P29475 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5473408 | 0.86 | MAOB (0.54) | MEP1BMAOBNOS1LMNAMEN1 | |
| SCHEMBL16366609 | 0.86 | MEP1B (0.65) | MEP1BMYCSMN1; SMN2 | |
| SCHEMBL30444148 | 0.86 | MEP1B (0.65) | MEP1BMYCSMN1; SMN2 | |
| SCHEMBL14143797 | 0.83 | LOXL2 (0.64) | MEP1BHPGDTSHRMEN1KMT2A | |
| SCHEMBL10131961 | 0.82 | NOS1 (0.51) | CYP19A1MAOBNOS1LMNAMAPK1 | |
| SCHEMBL22668307 | 0.82 | MEP1B (0.46) | MEP1BKMT2AHDAC8HDAC6MYC | |
| SCHEMBL8646446 | 0.81 | HDAC1 (0.57) | CYP19A1MAOBTSHRKMT2ARAB9A | |
| SCHEMBL4958280 | 0.80 | KAT6A (0.51) | MAOBLMNAMAPK1HPGDNPC1 | |
| SCHEMBL334537 | 0.80 | MAOB (0.53) | MAOBLMNAALDH1A1 | |
| SCHEMBL18095346 | 0.79 | TSHR (0.54) | MEP1BCYP19A1MAOBTSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112998-B1 | AMINE DERIVATIVES | POLA CHEM IND INC (JP) | 2004-12-08 | — | — | EP | disclosed |
| US-6586633-B1 | Antifungal agents | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2003-07-01 | — | — | US | disclosed |
| EP-1112998-A1 | AMINE DERIVATIVES | POLA CHEMICAL INDUSTRIES, INC. (JP) | 2001-07-04 | — | — | EP | disclosed |