Styrene

Styrene

SCHEMBL6906397

C=C(CC)C(=O)O.C=CC#N.C=Cc1ccccc1

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
AKR1C3 P42330 1/20 0.35
NPC1 O15118 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
MAPT P10636 1/20 0.35
RAB9A P51151 1/20 0.35
POLB P06746 1/20 0.35
MCL1 Q07820 1/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
PTGS2 P35354 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
CTSC P53634 1/20 0.32
LMNA P02545 2/20 0.32
HDAC3 O15379 1/20 0.32
PLIN1 O60240 1/20 0.32
PLIN5 Q00G26 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL4005348 0.97 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3NPC1SMN1; SMN2
Styrene SCHEMBL238870 0.91 ALDH1A1 (0.52) ALDH1A1TSHRAKR1C3NPC1MEN1
Styrene SCHEMBL8332408 0.90 ALDH1A1 (0.41) ALDH1A1TSHRAKR1C3NPC1SMN1; SMN2
Styrene SCHEMBL294651 0.87 ALDH1A1 (0.48) ALDH1A1TSHRAKR1C3NPC1MEN1
Styrene SCHEMBL183141 0.87 LMNA (0.41) ALDH1A1TSHRMEN1KMT2ALMNA
Styrene SCHEMBL7043418 0.87 ALDH1A1 (0.39) ALDH1A1TSHRAKR1C3NPC1SMN1; SMN2
Styrene SCHEMBL7699411 0.86 ALDH1A1 (0.47) ALDH1A1TSHRAKR1C3NPC1SMN1; SMN2
Styrene SCHEMBL3102461 0.86 ALDH1A1 (0.47) ALDH1A1TSHRAKR1C3NPC1MAPT
Styrene SCHEMBL4655474 0.86 ALDH1A1 (0.47) ALDH1A1TSHRAKR1C3NPC1MEN1
Styrene SCHEMBL10454759 0.85 ALDH1A1 (0.40) ALDH1A1TSHRAKR1C3NPC1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2520616-B1 SILICON-BASED IMPACT MODIFIER CONSISTING OF A GRAFT COPOLYMER HAVING A CORE-SHELL STRUCTURE, AND THERMOPLASTIC COMPOSITION HAVING SAME SAMSUNG SDI CO LTD (KR) 2017-04-26 EP claimed
EP-2520616-A1 SILICON-BASED IMPACT MODIFIER CONSISTING OF A GRAFT COPOLYMER HAVING A CORE-SHELL STRUCTURE, AND THERMOPLASTIC COMPOSITION HAVING SAME Cheil Industries Inc. (KR) 2012-11-07 EP claimed
US-20120264871-A1 Silicone-Based Impact Modifier Including a Graft Copolymer Having a Core-Shell Structure and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2012-10-18 US claimed
EP-1034726-A1 A method of connecting an anchoring piece of plastics material to a structural element of wood, anchoring piece, structural element and slatted bed base according to that method Recticel Bedding (Schweiz) GmbH (CH) 2000-09-13 EP claimed
EP-2520616-B1 SILICON-BASED IMPACT MODIFIER CONSISTING OF A GRAFT COPOLYMER HAVING A CORE-SHELL STRUCTURE, AND THERMOPLASTIC COMPOSITION HAVING SAME SAMSUNG SDI CO LTD (KR) 2017-04-26 EP disclosed
EP-2520616-A1 SILICON-BASED IMPACT MODIFIER CONSISTING OF A GRAFT COPOLYMER HAVING A CORE-SHELL STRUCTURE, AND THERMOPLASTIC COMPOSITION HAVING SAME Cheil Industries Inc. (KR) 2012-11-07 EP disclosed
US-20120264871-A1 Silicone-Based Impact Modifier Including a Graft Copolymer Having a Core-Shell Structure and Thermoplastic Resin Composition Including the Same CHEIL INDUSTRIES INC. (KR) 2012-10-18 US disclosed
EP-0771852-B1 Flame retardant thermoplastic composition containing aromatic polycarbonate resins and a rubber modified graft copolymer GEN ELECTRIC (US) 2004-02-25 EP disclosed
EP-1034726-A1 A method of connecting an anchoring piece of plastics material to a structural element of wood, anchoring piece, structural element and slatted bed base according to that method Recticel Bedding (Schweiz) GmbH (CH) 2000-09-13 EP disclosed
US-6001509-A TERPOLYMER OF ACRYLONITRILE, METHYL METHACRYLATE AND OLIGOOXYETHYLENE ETHYLETHER METHACRYLATE; AND A LIQUID ELECTROLYTE COMPOSED OF A LITHIUM SALT AND APROTIC SOLVENT; FORMS A THIN ELECTROLYTE FILM, GOOD IONIC CONDUCTIVITY SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 1999-12-14 US disclosed
EP-0853585-A4 CARTON HAVING BUCKLE-CONTROLLED BRIM CURL AND METHOD AND BLANK FOR FORMING THE SAME FORT JAMES CORP (US) 1999-09-08 EP disclosed
US-5868309-A PAPERBOARD CONTAINER, STYRENE-ACRYLIC DERIVATIVE LATEX COATING; DEFECT-FREE BRIM CURL FORT JAMES CORPORATION (US) 1999-02-09 US disclosed
WO-1997005024-A1 CARTON HAVING BUCKLE-CONTROLLED BRIM CURL AND METHOD AND BLANK FOR FORMING THE SAME JAMES RIVER CORPORATION OF VIRGINIA (US) 1997-02-13 WO disclosed
US-5536780-A THERMOPLASTIC BLENDS GENERAL ELECTRIC COMPANY (US) 1996-07-16 US disclosed
EP-0714949-A2 Processes, thermoplastic compositions and emulsion graft copolymer utilizing a polyacid GENERAL ELECTRIC COMPANY (US) 1996-06-05 EP disclosed
EP-0714943-A2 Impact modifier vinyl chloride resin composition, and graft copolymer compositions GENERAL ELECTRIC COMPANY (US) 1996-06-05 EP disclosed
US-5441816-A Superstrate comprising vinyl chloride polymer, butyl acrylate rubber graft polymer, titanium dioxide; substrate comprising vinyl chloride polymer, butadiene rubber graft polymer, titanium dioxide; outdoor construction materials GENERAL ELECTRIC COMPANY (US) 1995-08-15 US disclosed
US-5415921-A Protective layer GENERAL ELECTRIC COMPANY (US) 1995-05-16 US disclosed
EP-0639609-A1 Process for the manufacture of low gloss resins GENERAL ELECTRIC COMPANY (US) 1995-02-22 EP disclosed
EP-0622184-A1 Coextruded multilayer vinyl chloride polymer laminates GENERAL ELECTRIC COMPANY (US) 1994-11-02 EP disclosed