Styrene

Styrene

SCHEMBL4005348

C=C(CC)C(=O)O.C=CC#N.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.40

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.40
NPC1 O15118 2/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
RAB9A P51151 1/20 0.33
AKR1C3 P42330 1/20 0.33
POLB P06746 1/20 0.33
PTGS2 P35354 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
MCL1 Q07820 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TAS1R3 Q7RTX0 1/20 0.31
TAS1R1 Q7RTX1 1/20 0.31
HPGD P15428 1/20 0.31
CTSC P53634 1/20 0.31
LMNA P02545 2/20 0.31
HDAC3 O15379 1/20 0.31
PLIN1 O60240 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL6906397 0.97 ALDH1A1 (0.42) ALDH1A1TSHRNPC1MAPTSMN1; SMN2
Styrene SCHEMBL294651 0.91 ALDH1A1 (0.48) ALDH1A1TSHRNPC1AKR1C3PTGS2
Styrene SCHEMBL7043418 0.90 ALDH1A1 (0.39) ALDH1A1TSHRNPC1MAPTSMN1; SMN2
Styrene SCHEMBL238870 0.88 ALDH1A1 (0.52) ALDH1A1TSHRNPC1AKR1C3PTGS2
Styrene SCHEMBL8332408 0.87 ALDH1A1 (0.41) ALDH1A1TSHRNPC1MAPTSMN1; SMN2
Styrene SCHEMBL4116570 0.85 ALDH1A1 (0.35) ALDH1A1TSHRNPC1MAPTSMN1; SMN2
Styrene SCHEMBL28022328 0.85 ALDH1A1 (0.45) ALDH1A1TSHRNPC1MAPTSMN1; SMN2
Styrene SCHEMBL465498 0.85 ALDH1A1 (0.45) ALDH1A1TSHRNPC1MAPTSMN1; SMN2
Acrylonitrile SCHEMBL8743878 0.84 ALOX15 (0.36) ALDH1A1TSHR
Styrene SCHEMBL183141 0.84 LMNA (0.41) ALDH1A1TSHRMEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022050055-A1 MASK MEMBER FOR COLOR MEASUREMENT DEVICE, COLOR MEASUREMENT DEVICE, AND COLOR MEASUREMENT METHOD 大日精化工業株式会社 2022-03-10 WO claimed
US-20210345600-A1 CRYOPRESERVATION OF CELL MONOLAYERS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2021-11-11 US claimed
EP-3592532-B1 CORE-SHELL FILAMENT FOR PRINTING SMOOTH FDM 3D ITEMS SIGNIFY HOLDING BV (NL) 2021-07-07 EP claimed
US-11007707-B2 Method for manufacturing a 3D item SIGNIFY HOLDING B.V. (NL) 2021-05-18 US claimed
EP-3794079-A1 SURFACES RESISTANT TO BACTERIAL ADHESION Evonik Canada Inc. (CA) 2021-03-24 EP claimed
EP-3740537-A1 POLYOL POLYESTER AND POLYHYDROXY ALKANE BLENDS WITH POLAR POLYMERS Arkema Inc. (US) 2020-11-25 EP claimed
US-20200354560-A1 POLYOL POLYESTER AND POLYHYDROXY ALKANE BLENDS WITH POLAR POLYMERS ALTER DOMUS (US) LLC 2020-11-12 US claimed
WO-2020037416-A1 CRYOPRESERVATION OF CELL MONOLAYERS THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2020-02-27 WO claimed
WO-2019218088-A1 SURFACES RESISTANT TO BACTERIAL ADHESION Evonik Canada Inc. (CA) 2019-11-21 WO claimed
WO-2019143481-A1 POLYOL POLYESTER AND POLYHYDROXY ALKANE BLENDS WITH POLAR POLYMERS ARKEMA INC. (US) 2019-07-25 WO claimed
EP-2627235-B1 A UNIVERSAL CAP MEDIVATORS INC (US) 2019-02-20 EP claimed
WO-2018162268-A1 CORE-SHELL FILAMENT FOR PRINTING SMOOTH FDM 3D ITEMS PHILIPS LIGHTING HOLDING B.V. (NL) 2018-09-13 WO claimed
EP-4400432-A2 SYSTEM FOR LOW-TEMPERATURE STORAGE OF A PHARMACEUTICAL COMPOSI-TION, LIQUID COMPOSITION, METHOD AND USES SCHOTT Pharma Schweiz AG (CH) 2024-07-17 EP disclosed
EP-4380670-A1 CHECK VALVE Carefusion 303 Inc. (US) 2024-06-12 EP disclosed
US-20240041698-A1 SYSTEM FOR LOW-TEMPERATURE STORAGE OF A PHARMACEUTICAL COMPOSITION, LIQUID COMPOSITION, METHOD AND USES SCHOTT PHARMA SCHWEIZ AG (CH) 2024-02-08 US disclosed
EP-4313211-A1 SYSTEM FOR LOW-TEMPERATURE STORAGE OF A PHARMACEUTICAL COMPOSITION, LIQUID COMPOSITION, METHOD AND USES SCHOTT Pharma Schweiz AG (CH) 2024-02-07 EP disclosed
US-20080261261-A1 System/unit and method employing a plurality of magnetoelastic sensor elements for automatically quantifying parameters of whole blood and platelet-rich plasma KMG2 SENSORS CORPORATION 2008-10-23 US disclosed
US-5532054-A Molding material MITSUI TOATSU CHEMICALS, INC. (JP) 1996-07-02 US disclosed
EP-0360430-B1 Molding material MITSUI TOATSU CHEMICALS (JP) 1995-06-14 EP disclosed
EP-0360430-A2 Molding material MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210345600-A1 CRYOPRESERVATION OF CELL MONOLAYERS HPSE, CD44, LIPG ALDH1A1 2599/4885TSHR 3657/4885NPC1 1879/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.