Styrene

Styrene

SCHEMBL7043418

C=C(CCC)C(=O)O.C=CC#N.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.39

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
LMNA P02545 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
SMN1; SMN2 Q16637 3/20 0.34
MAPT P10636 2/20 0.34
KMT2A Q03164 2/20 0.34
CES2 O00748 1/20 0.34
CES1 P23141 1/20 0.34
TAS1R3 Q7RTX0 1/20 0.33
TAS1R1 Q7RTX1 1/20 0.33
NPC1 O15118 2/20 0.33
POLB P06746 1/20 0.33
RAB9A P51151 1/20 0.33
HDAC3 O15379 1/20 0.33
HPGD P15428 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
AKR1C3 P42330 1/20 0.33
ADORA2A P29274 1/20 0.32
ADORA1 P30542 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL8332408 0.97 ALDH1A1 (0.41) ALDH1A1TSHRLMNATDP1SMN1; SMN2
Styrene SCHEMBL9879339 0.91 ALDH1A1 (0.47) ALDH1A1TSHRLMNATDP1SMN1; SMN2
Styrene SCHEMBL4005348 0.90 ALDH1A1 (0.40) ALDH1A1TSHRLMNASMN1; SMN2MAPT
Styrene SCHEMBL183141 0.89 LMNA (0.41) ALDH1A1TSHRLMNATDP1KMT2A
Styrene SCHEMBL1628104 0.88 ALDH1A1 (0.50) ALDH1A1TSHRLMNATDP1SMN1; SMN2
Styrene SCHEMBL6906397 0.87 ALDH1A1 (0.42) ALDH1A1TSHRLMNASMN1; SMN2MAPT
Styrene SCHEMBL677845 0.86 ALDH1A1 (0.34) ALDH1A1TSHRLMNATDP1MAPT
Styrene SCHEMBL3430856 0.85 LMNA (0.39) ALDH1A1TSHRLMNATDP1KMT2A
Styrene SCHEMBL465498 0.84 ALDH1A1 (0.45) ALDH1A1TSHRTDP1SMN1; SMN2MAPT
Styrene SCHEMBL28022328 0.84 ALDH1A1 (0.45) ALDH1A1TSHRTDP1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9643360-B2 Self-hardening material and process for layerwise formation of models VOXELJET AG (DE) 2017-05-09 US claimed
US-20040241370-A1 Adhesive composition and adhesive tape for mounting a mirror ROYAL ADHESIVES AND SEALANTS, LLC 2004-12-02 US claimed
WO-2004081131-A2 ADHESIVE COMPOSITION AND ADHESIVE TAPE FOR MOUNTING A MIRROR ROYAL ADHESIVES AND SEALANTS, LLC (US) 2004-09-23 WO claimed
US-20040241370-A1 Adhesive composition and adhesive tape for mounting a mirror ROYAL ADHESIVES AND SEALANTS, LLC 2004-12-02 US disclosed
WO-2004081131-A2 ADHESIVE COMPOSITION AND ADHESIVE TAPE FOR MOUNTING A MIRROR ROYAL ADHESIVES AND SEALANTS, LLC (US) 2004-09-23 WO disclosed