Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CFD | P00746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44032 | 0.82 | MMP2 (0.49) | CYP4F2CYP4A11ALDH1A1KDM4EMMP2 | |
| SCHEMBL1901977 | 0.80 | ALDH1A1 (0.45) | CYP4F2CYP4A11ALDH1A1KDM4EMMP2 | |
| SCHEMBL6907476 | 0.77 | CYP4F2 (0.43) | CYP4F2CYP4A11ALDH1A1KDM4EMMP2 | |
| SCHEMBL6904042 | 0.77 | NPSR1 (0.44) | CYP4F2CYP4A11KDM4EPTGS2 | |
| SCHEMBL4842042 | 0.76 | CYP3A4 (0.47) | ALDH1A1KDM4EHSD17B10CYP3A4GAA | |
| SCHEMBL24716315 | 0.75 | CYP4F2 (0.42) | CYP4F2CYP4A11ALDH1A1KDM4EMMP2 | |
| SCHEMBL344663 | 0.75 | CYP4F2 (0.55) | CYP4F2CYP4A11ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13034143 | 0.74 | HSD17B10 (0.41) | CYP4F2CYP4A11ALDH1A1KDM4EMMP2 | |
| SCHEMBL29140951 | 0.74 | CYP4F2 (0.53) | CYP4F2CYP4A11ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL11308643 | 0.73 | CFD (0.58) | CYP4F2CYP4A11ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | claimed |
| US-20040171864-A1 | Fluorinated aromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171864-A1 | Fluorinated aromatics | AFF1, AFF2, AFF4 | CYP4F2 37/4885CYP4A11 196/4885ALDH1A1 1595/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.