Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7197821 | 1.00 | NPC1 (0.32) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL28051360 | 0.96 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| Hydrochloric Acid SCHEMBL8577642 | 0.96 | NPC1 (0.31) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL7575488 | 0.89 | — | — | |
| SCHEMBL6254543 | 0.86 | — | — | |
| SCHEMBL1025348 | 0.78 | NPC1 (0.32) | NPC1HPGDMAPK1HTTRAB9A | |
| SCHEMBL11022343 | 0.77 | — | — | |
| SCHEMBL6252137 | 0.77 | — | — | |
| SCHEMBL1753874 | 0.76 | — | — | |
| SCHEMBL7624298 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105315389-A | Novel bis(1-butyl, 3-methyl)cyclopentadienyl metallocene catalyst and preparation method thereof | SUZHOU APAC BIOLOG SCIENCE & TECHNOLOGY CO LTD | 2016-02-10 | — | — | CN | claimed |
| EP-0727431-B1 | Process for preparing alkylsubtituted cyclopentadienyl metallocene compounds | ALBEMARLE CORP (US) | 2002-10-02 | — | — | EP | claimed |
| CN-120058451-A | Preparation method of substituted cyclopentadiene | 中化学科学技术研究有限公司 | 2025-05-30 | — | — | CN | disclosed |
| EP-3696184-B1 | POLYOLEFIN CATALYST AND METHOD FOR PREPARING POLYOLEFIN USING SAME | LOTTE CHEMICAL CORP (KR) | 2024-10-02 | — | — | EP | disclosed |
| US-12098158-B2 | Transition metal compound, catalyst composition and method for preparing polypropylene using the same | LG CHEM, LTD. (KR) | 2024-09-24 | — | — | US | disclosed |
| CN-113316583-B | Transition metal compound, catalyst composition, and method for preparing polypropylene using same | 株式会社LG化学 | 2024-03-19 | — | — | CN | disclosed |
| EP-3546490-B1 | POLYOLEFIN CATALYST AND METHOD FOR PREPARING POLYOLEFIN BY USING SAME | LOTTE CHEMICAL CORP (KR) | 2024-03-06 | — | — | EP | disclosed |
| US-11639435-B2 | Method for preparing high-melt-strength polypropylene resin | LOTTE CHEMICAL CORPORATION (KR) | 2023-05-02 | — | — | US | disclosed |
| CN-109983040-B | Polyolefin catalyst and method for preparing polyolefin using the same | 乐天化学株式会社 | 2022-12-23 | — | — | CN | disclosed |
| US-11359040-B2 | Polyolefin catalyst and method for preparing polyolefin by using same | LOTTE CHEMICAL CORPORATION (KR) | 2022-06-14 | — | — | US | disclosed |
| US-11312796-B2 | Polyolefin catalyst and method for preparing polyolefin using same | LOTTE CHEMICAL CORPORATION (KR) | 2022-04-26 | — | — | US | disclosed |
| EP-0969010-A2 | Transition metal compound and catalyst containing the same for polymerization of olefins | Japan Polyolefins Co., Ltd. (JP) | 2000-01-05 | — | — | EP | disclosed |
| US-5856541-A | Process for preparing 1 3-disubstituted cyclopentadienyl ligands and transition metal complexes thereof | WITCO GMBH (DE) | 1999-01-05 | — | — | US | disclosed |
| EP-0729967-B1 | Process for the preparation of transition metal complexes with 1,3-disubstituted cyclopentadienyl ligands | WITCO GMBH (DE) | 1998-08-12 | — | — | EP | disclosed |
| WO-1998015510-A1 | PREPARATION OF ALKYLCYCLOPENTADIENES | ALBEMARLE CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |
| US-5569746-A | Process for preparing alkylsubstituted cyclopentadienyl metallocene compounds | ALBEMARLE CORPORATION (US) | 1996-10-29 | — | — | US | disclosed |
| EP-0729967-A1 | Process for the preparation of transition metal complexes with 1,3-disubstituted cyclopentadienyl ligands | Witco GmbH (DE) | 1996-09-04 | — | — | EP | disclosed |
| EP-0727431-A2 | Process for preparing alkylsubtituted cyclopentadienyl metallocene compounds | ALBEMARLE CORPORATION (US) | 1996-08-21 | — | — | EP | disclosed |
| US-5545785-A | Process for preparing biscyclopentadienyl compounds | WITCO GMBH (DE) | 1996-08-13 | — | — | US | disclosed |
| EP-0665234-A1 | Process for the preparation of bicyclopentadienyl compounds | Witco GmbH (DE) | 1995-08-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12098158-B2 | Transition metal compound, catalyst composition and method for preparing polypropylene using the same | PMS2, POP1, MUS81 | NPC1 4426/4885HPGD 833/4885MAPK1 969/4885 |
| US-11359040-B2 | Polyolefin catalyst and method for preparing polyolefin by using same | SDC1, FDFT1, AUP1 | NPC1 2974/4885HPGD 4387/4885MAPK1 552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.