SCHEMBL6907008

SCHEMBL6907008

CC(=O)Oc1cccc2c1C(=O)c1ccccc1C2

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.50
MAOA P21397 1/20 0.49
ALDH1A1 P00352 9/20 0.48
MAPT P10636 6/20 0.48
KDM4E B2RXH2 6/20 0.48
MEN1 O00255 4/20 0.48
KMT2A Q03164 4/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
PKM P14618 2/20 0.48
HTR2A P28223 2/20 0.48
HPGD P15428 2/20 0.48
LMNA P02545 2/20 0.48
USP2 O75604 2/20 0.48
MAPK1 P28482 2/20 0.48
ABCC4 O15439 1/20 0.48
TP53 P04637 1/20 0.48
HSP90AA1 P07900 1/20 0.48
CHRM2 P08172 1/20 0.48
HSP90AB1 P08238 1/20 0.48
HTR1A P08908 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28206950 0.89 HTR2A (0.47) TTRMAOAALDH1A1MAPTKDM4E
SCHEMBL1645515 0.89 ALDH1A1 (0.50) TTRALDH1A1MAPTKDM4EMEN1
SCHEMBL1645434 0.82 ALDH1A1 (0.65) TTRMAOAALDH1A1MAPTKDM4E
SCHEMBL6906412 0.81 ALDH1A1 (0.58) MAOAALDH1A1MAPTKDM4EMEN1
SCHEMBL343377 0.81 ALDH1A1 (0.60) TTRMAOAALDH1A1MAPTKDM4E
SCHEMBL11101186 0.80 TTR (0.72) TTRMAOAALDH1A1MAPTKDM4E
SCHEMBL28384518 0.78 MAOA (0.55) MAOAALDH1A1MAPTKDM4EMEN1
SCHEMBL6770157 0.78 MAOA (0.50) MAOAALDH1A1MAPTKDM4EMEN1
SCHEMBL497339 0.77 MAPT (0.60) TTRMAOAALDH1A1MAPTKDM4E
SCHEMBL29551111 0.77 MAPT (0.60) TTRMAOAALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6815481-B2 FUSED DIBENZO THERMAL STABILIZERS SUCH AS ANTHRACENE, XANTHENE AND ANTHRONE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-11-09 US disclosed
US-20020032256-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-03-14 US disclosed