Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11271210 | 0.92 | ALDH1A1 (0.54) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL6907008 | 0.81 | TTR (0.50) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL3359950 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL7833003 | 0.76 | MAOA (0.59) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E | |
| SCHEMBL11101186 | 0.75 | TTR (0.72) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL3809960 | 0.75 | ALDH1A1 (1.00) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| Acetic Acid SCHEMBL343375 | 0.74 | MAPT (0.63) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL343281 | 0.74 | KEAP1 (0.53) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL11217585 | 0.73 | ALDH1A1 (0.47) | ALDH1A1MAPTSMN1; SMN2KMT2ARAB9A | |
| SCHEMBL343740 | 0.73 | MAOA (0.47) | ALDH1A1MAPTSMN1; SMN2RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-55108834-A | — | — | None | — | — | JP | disclosed |
| EP-2393797-B1 | PROCESS FOR PREPARING OLOPATADINE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZACH SYSTEM SPA (IT) | 2016-04-20 | — | — | EP | disclosed |
| US-8835655-B2 | Process for preparing olopatadine and/or a pharmaceutically acceptable salt thereof | ZACH SYSTEM S.P.A (IT) | 2014-09-16 | — | — | US | disclosed |
| US-20120016138-A1 | PROCESS FOR PREPARING OLOPATADINE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | ZACH SYSTEM S.P.A. (IT) | 2012-01-19 | — | — | US | disclosed |
| EP-0119540-B1 | SUBSTITUTED ALKYLAMINE DERIVATIVES OF 6,11-DIHYDRO-11-OXODIBENZ (B,E)-OXEPINS, A PROCESS FOR THE PREPARATION AND INTERMEDIATES THEREOF AND THEIR USE AS MEDICAMENTS | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1990-08-22 | — | — | EP | disclosed |
| US-4751238-A | ANALGESICS, ANTIINFLAMMATORY AGENT | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1988-06-14 | — | — | US | disclosed |
| US-4576960-A | 6,11-Dihydro-11-oxo-dibenz[b,e]oxepin derivatives | HOECHST ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1986-03-18 | — | — | US | disclosed |
| US-4515946-A | 6,11-Dihydro-11-oxo-dibenz-[b,e]oxepin derivatives | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0082521-A1 | 6,11-Dihydro-11,-oxo-dibenz(b,e)-oxepin derivatives, methods for their preparation, pharmaceutical compositions containing the same and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1983-06-29 | — | — | EP | disclosed |
| JP-S55108834-A | PREPARATION OF (2-CARBOXYBENZYLOXY)-PHENYLACETATIC ACID | DAI ICHI SEIYAKU CO LTD | 1980-08-21 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120016138-A1 | PROCESS FOR PREPARING OLOPATADINE AND/OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | QDPR, OPRD1, O60361 | ALDH1A1 1057/4885MAPT 2063/4885SMN1; SMN2 1726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.