SCHEMBL6907113

SCHEMBL6907113

CC1COC(Cc2ccccc2)O1

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.53
TAAR1 Q96RJ0 2/20 0.38
SLC6A2 P23975 1/20 0.38
SLC6A4 P31645 1/20 0.38
SLC6A3 Q01959 1/20 0.38
NOS1 P29475 2/20 0.37
NOS2 P35228 2/20 0.37
DDB1 Q16531 1/20 0.37
CRBN Q96SW2 1/20 0.37
GBA1 P04062 1/20 0.35
MAOB P27338 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30229478 0.82 SLC6A2 (0.39) L3MBTL1SLC6A2SLC6A4SLC6A3GBA1
SCHEMBL996908 0.82 L3MBTL1 (0.50) L3MBTL1TAAR1SLC6A2SLC6A4SLC6A3
Benzyl Benzoate SCHEMBL7194408 0.82 KMT2A (0.57) L3MBTL1SLC6A2SLC6A3
SCHEMBL25836448 0.81 SLC6A2 (0.40) L3MBTL1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL3100127 0.81 SLC6A2 (0.40) L3MBTL1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL3100122 0.81 SLC6A2 (0.40) L3MBTL1TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL11734399 0.78 LTB4R (0.41) TAAR1SLC6A2SLC6A4SLC6A3DDB1
SCHEMBL1673315 0.77 TAAR1 (0.35) TAAR1SLC6A2SLC6A4SLC6A3
SCHEMBL216883 0.75 SLC6A2 (0.39) TAAR1SLC6A2SLC6A4SLC6A3GBA1
SCHEMBL873745 0.74 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3NOS1NOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0435059-B1 Retroviral protease inhibitors HOECHST AG (DE) 1997-11-05 EP claimed
US-5663139-A VIRICIDE OLIGOPEPTIDES HOECHST AKTIENGESELLSCHAFT (DE) 1997-09-02 US claimed
EP-0688314-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP claimed
WO-1994021604-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-29 WO claimed
EP-0410278-B1 Renin inhibiting aminooligohydroxy-derivatives HOECHST AG (DE) 1994-01-19 EP claimed
US-5169841-A Enzyme inhibitors, hypotensive agents, high enteral bioauailability HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-08 US claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
US-11758933-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2023-09-19 US disclosed
EP-3368542-B1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2022-06-22 EP disclosed
US-11357246-B2 High intensity sweeteners FIRMENICH INCORPORATED (US) 2022-06-14 US disclosed
US-20210227863-A1 HIGH INTENSITY SWEETENERS SENOMYX, INC. 2021-07-29 US disclosed
CN-108473484-B Compounds useful as TRPM8 modulators 弗门尼舍公司 2021-06-29 CN disclosed
EP-3356356-B1 COMPOUNDS USEFUL AS MODULATORS OF TRPM8 FIRMENICH INCORPORATED (US) 2021-05-26 EP disclosed
US-5629431-A Inhibitors of retroviral proteases HOECHST AKTIENGESELLSCHAFT (DE) 1997-05-13 US disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
EP-0688314-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1995-12-27 EP disclosed
WO-1994021604-A1 PRODRUG DERIVATIVES OF ENZYME INHIBITORS WITH HYDROXYL GROUPS, METHODS OF PREPARING THEM AND THEIR USE HOECHST AKTIENGESELLSCHAFT (DE) 1994-09-29 WO disclosed
US-5169841-A Enzyme inhibitors, hypotensive agents, high enteral bioauailability HOECHST AKTIENGESELLSCHAFT (DE) 1992-12-08 US disclosed
EP-0254078-B1 PYRAN DERIVATIVES BASF Aktiengesellschaft (DE) 1991-02-06 EP disclosed
EP-0254078-A1 Pyran derivatives BASF Aktiengesellschaft (DE) 1988-01-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 L3MBTL1 4816/4885TAAR1 942/4885SLC6A2 748/4885
US-11357246-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 L3MBTL1 4816/4885TAAR1 942/4885SLC6A2 748/4885
US-20210227863-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 L3MBTL1 4816/4885TAAR1 942/4885SLC6A2 748/4885
US-11758933-B2 High intensity sweeteners TAS2R40, TAS2R60, TAS1R1 L3MBTL1 4816/4885TAAR1 942/4885SLC6A2 748/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.