Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.46 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL1767861 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| Acetic Acid SCHEMBL8675920 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| Acetic Acid SCHEMBL324428 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| Acetic Acid SCHEMBL615639 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| Acetic Acid SCHEMBL4741906 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| Acetic Acid SCHEMBL1929473 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| Acetic Acid SCHEMBL3260062 | 1.00 | CPB2 (0.53) | CPB2CA2GRIK1GRIK2GPR84 | |
| SCHEMBL25341592 | 0.94 | CPB2 (0.58) | CPB2CA2GRIK1GRIK2GPR84 | |
| SCHEMBL571313 | 0.94 | CPB2 (0.58) | CPB2CA2GRIK1GRIK2GPR84 | |
| SCHEMBL19148651 | 0.94 | CPB2 (0.58) | CPB2CA2GRIK1GRIK2GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11647749-B2 | Fungicidal compositions | SYNGENTA PARTICIPATIONS AG (CH) | 2023-05-16 | — | — | US | disclosed |
| US-20230113346-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION LLC (US) | 2023-04-13 | — | — | US | disclosed |
| US-20200163337-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2020-05-28 | — | — | US | disclosed |
| US-10575523-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION LLC (US) | 2020-03-03 | — | — | US | disclosed |
| US-20190053491-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2019-02-21 | — | — | US | disclosed |
| US-10143201-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2018-12-04 | — | — | US | disclosed |
| US-20170202220-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2017-07-20 | — | — | US | disclosed |
| US-9642365-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160192655-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA CROP PROTECTION, LLC (US) | 2016-07-07 | — | — | US | disclosed |
| US-9314022-B2 | Fungicidal compositions | SYNGENTA CROP PROTECTION, LLC (US) | 2016-04-19 | — | — | US | disclosed |
| EP-2193714-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193715-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193716-A1 | Fungicidal Compositions | Syngenta Participations AG (CH) | 2010-06-09 | — | — | EP | disclosed |
| EP-2193717-A1 | Fungicidal Compositions | Sygenta Participations AG. (CH) | 2010-06-09 | — | — | EP | disclosed |
| US-7732469-B2 | for controlling or preventing infestation of plants by phytopathogenic microorganisms, preferably fungi | SYNGENTA CROP PROTECTION, INC. (US) | 2010-06-08 | — | — | US | disclosed |
| EP-2150113-A1 | FUNGICIDAL COMPOSITIONS | Syngeta Participations AG (CH) | 2010-02-10 | — | — | EP | disclosed |
| WO-2008131901-A1 | FUNGICIDAL COMPOSITIONS | SYNGENTA PARTICIPATIONS AG (CH) | 2008-11-06 | — | — | WO | disclosed |
| US-20080227835-A1 | Heterocyclic Amide Derivatives Useful as Microbiocides | SYNGENTA CROP PROTECTION, INC. (US) | 2008-09-18 | — | — | US | disclosed |
| EP-1940813-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | Syngeta Participations AG (CH) | 2008-07-09 | — | — | EP | disclosed |
| WO-2007048556-A1 | HETEROCYCLIC AMIDE DERIVATIVES USEFUL AS MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2007-05-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11647749-B2 | Fungicidal compositions | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-20190053491-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-20160192655-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-10143201-B2 | Fungicidal compositions | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-20170202220-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-10575523-B2 | Fungicidal compositions | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-20230113346-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-20200163337-A1 | FUNGICIDAL COMPOSITIONS | BROX, RER1, BLVRB | CPB2 3284/4885CA2 3451/4885GRIK1 1677/4885 |
| US-20080227835-A1 | Heterocyclic Amide Derivatives Useful as Microbiocides | CBR3, CBR1, CYP8B1 | CPB2 3063/4885CA2 1228/4885GRIK1 3031/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.