SCHEMBL6908263

SCHEMBL6908263

C=C[SiH](c1ccccc1)[Zr](Cl)(Cl)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL438073 0.82 HTR6 (0.30)
SCHEMBL216461 0.80 HTR6 (0.31)
SCHEMBL445165 0.79
SCHEMBL216045 0.78 SIGMAR1 (0.31)
SCHEMBL437345 0.75 HTR6 (0.31)
SCHEMBL28978370 0.73 HTR6 (0.33)
SCHEMBL60272 0.73 HTR6 (0.33)
SCHEMBL441382 0.73 HTR6 (0.30)
SCHEMBL6725601 0.72 HTR6 (0.32)
SCHEMBL439955 0.72 HTR2A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5914376-A Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof TARGOR GMBH (DE) 1999-06-22 US claimed
EP-0610852-B1 Process for preparing cyclo-olefin polymers HOECHST AG (DE) 1997-05-07 EP claimed
US-5545829-A Process for preparing cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US claimed
US-6747077-B2 HINDERED AMINE CIBA SPECIALTY CHEMICALS CORPORATION 2004-06-08 US disclosed
US-6512029-B1 Stabilized metallocene polyolefins CIBA SPECIALTY CHEMICALS CORPORATION 2003-01-28 US disclosed
US-20020128406-A1 PROCESS FOR POLYMERIZING UNSATURATED POLYALKYLPIPERIDINES WILEN CARL-ERIC MAGNUS (FI) 2002-09-12 US disclosed
US-20020077394-A1 Stabilized metallocene polypropylene CIBA SPECIALTY CHEMICALS CORP. 2002-06-20 US disclosed
US-20020013217-A1 CATALYST FOR THE POLYMERIZATION OF OLEFINS, PROCESS FOR ITS PREPARATION AND ITS USE HANS-FRIEDRICH HERRMANN 2002-01-31 US disclosed
US-5955522-A Process for the preparation of stabilized olefin polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-09-21 US disclosed
US-5942586-A Catalyst for the polymerization of olefins, process for its preparation and its use TARGOR GMBH (DE) 1999-08-24 US disclosed
US-5914376-A Catalyst for the polymerization of olefins, process for the preparation thereof, and use thereof TARGOR GMBH (DE) 1999-06-22 US disclosed
US-5703149-A Process for the preparation of stabilized olefin polymers CIBA SPECIALTY CHEMICALS CORPORATION (US) 1997-12-30 US disclosed
EP-0567952-B1 Olefin polymerization catalyst, process for its preparation, and its use HOECHST AG (DE) 1997-12-03 EP disclosed
US-5614455-A Olefin polymerization catalyst, process for its preparation, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1997-03-25 US disclosed
US-5578537-A Olefin polymerization catalyst process for its preparation and its use HOECHST AKTIENGESELLSCHAFT (DE) 1996-11-26 US disclosed
US-5545829-A Process for preparing cycloolefin copolymers HOECHST AKTIENGESELLSCHAFT (DE) 1996-08-13 US disclosed
EP-0578838-A1 Olefin polymerization catalyst, process for its preparation, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1994-01-19 EP disclosed
EP-0567952-A1 Olefin polymerization catalyst, process for its preparation, and its use HOECHST AKTIENGESELLSCHAFT (DE) 1993-11-03 EP disclosed
US-5081322-A Metallocene and Aluminoxane Polymerization Catalysts HOECHST AKTIENGESELLSCHAFT (DE) 1992-01-14 US disclosed