Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 13/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6907625 | 0.90 | CLPP (0.42) | CLPPMEN1KMT2AGNRHR | |
| SCHEMBL14152041 | 0.86 | CLPP (0.50) | CLPPKCNH2 | |
| SCHEMBL2303716 | 0.86 | CLPP (0.42) | CLPPKCNH2MEN1KMT2AATM | |
| SCHEMBL2301441 | 0.84 | MAPT (0.42) | KCNH2MEN1KMT2AGNRHR | |
| SCHEMBL6908946 | 0.83 | CLPP (0.37) | CLPPMEN1KMT2AATM | |
| SCHEMBL6909785 | 0.82 | BRS3 (0.44) | CLPPKCNH2ATMCYP3A4 | |
| SCHEMBL2302430 | 0.82 | MAPT (0.41) | CLPPKCNH2KMT2A | |
| SCHEMBL6911686 | 0.81 | MEN1 (0.51) | CLPPMEN1KMT2AATM | |
| SCHEMBL2301165 | 0.80 | CLPP (0.50) | CLPPMEN1KMT2AATM | |
| SCHEMBL2355004 | 0.79 | CLPP (0.47) | CLPPMEN1KMT2AATMRCE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101804-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |