Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 9/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GNRHR | P30968 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909385 | 0.90 | CLPP (0.40) | CLPPMEN1KMT2AGNRHR | |
| SCHEMBL6908946 | 0.88 | CLPP (0.37) | CLPPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2300073 | 0.87 | MEN1 (0.54) | CLPPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2337803 | 0.86 | KDM4E (0.54) | CLPPKMT2ADRD4DRD2DRD3 | |
| SCHEMBL2301395 | 0.85 | CLPP (0.57) | CLPPDRD4DRD2DRD3 | |
| SCHEMBL2301165 | 0.85 | CLPP (0.50) | CLPPMEN1KMT2A | |
| SCHEMBL6907289 | 0.84 | GABRA1 (0.43) | CLPPDRD2KDM4E | |
| SCHEMBL6911686 | 0.84 | MEN1 (0.51) | CLPPMEN1KMT2ADRD4DRD2 | |
| SCHEMBL6909785 | 0.83 | BRS3 (0.44) | CLPPDRD2DRD3KDM4EALDH1A1 | |
| SCHEMBL6909376 | 0.83 | KMT2A (0.51) | CLPPKMT2ADRD4DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101804-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |