Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLPP | Q16740 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6910461 | 0.93 | MEN1 (0.37) | CLPPMEN1KMT2AATMPRMT5 | |
| SCHEMBL6907625 | 0.88 | CLPP (0.42) | CLPPMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL2303402 | 0.86 | CLPP (0.49) | CLPP | |
| SCHEMBL6907289 | 0.85 | GABRA1 (0.43) | CLPPCHRNB2CHRNA4KDM4E | |
| SCHEMBL2305149 | 0.84 | GABRA1 (0.46) | CLPPMEN1KMT2AATMPRMT5 | |
| SCHEMBL6909385 | 0.83 | CLPP (0.40) | CLPPMEN1KMT2AATM | |
| SCHEMBL2304833 | 0.80 | CLPP (0.41) | CLPPMEN1KMT2AATMKDM4E | |
| SCHEMBL2346966 | 0.79 | CLPP (0.47) | CLPP | |
| SCHEMBL2306533 | 0.79 | PRMT5 (0.41) | CLPPMEN1KMT2AATMPRMT5 | |
| SCHEMBL6909785 | 0.79 | BRS3 (0.44) | CLPPATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101804-A1 | PYRAZOLO PIPERIDINE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2011-08-25 | — | — | WO | disclosed |