SCHEMBL6909422

SCHEMBL6909422

CO[SiH](OC)C(CC(C)C)C1CC2CCC1C2

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
ALDH1A1 P00352 3/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
POLB P06746 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6905868 0.74 ALDH1A1 (0.36) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL6907161 0.71
SCHEMBL27567334 0.70 LMNA (0.33) LMNAHPGDSMN1; SMN2ALDH1A1KMT2A
SCHEMBL6903166 0.70 ALDH1A1 (0.33) LMNAHPGDSMN1; SMN2ALDH1A1
SCHEMBL6907766 0.68 MMP1 (0.31)
SCHEMBL6908899 0.68 SMN1; SMN2 (0.32) SMN1; SMN2
SCHEMBL6909418 0.68 HPGD (0.34) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL19655056 0.67 HPGD (0.41) LMNAHPGDSMN1; SMN2ALDH1A1MEN1
SCHEMBL6910647 0.67 SHBG (0.34) SMN1; SMN2
SCHEMBL6911017 0.67 SHBG (0.34) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6689849-B1 Catalyst for bulk polymerization, catalyst for vapor phase polymerization, method of polymerization using these, and olefin polymer obtained with these IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-02-10 US disclosed
EP-1188774-A1 CATALYST FOR BULK POLYMERIZATION, CATALYST FOR VAPOR PHASE POLYMERIZATION, METHOD OF POLYMERIZATION USING THESE, AND OLEFIN POLYMER OBTAINED WITH THESE IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2002-03-20 EP disclosed
EP-1094083-A2 Catalyst for olefin polymerization, method for producing olefin polymer, and olefin polymer IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2001-04-25 EP disclosed