SCHEMBL690946

SCHEMBL690946

O=C(Cl)C1(C(F)(F)F)CC1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25325201 0.91 DGAT1 (0.43) DGAT1
SCHEMBL1939082 0.90 DGAT1 (0.41) DGAT1
SCHEMBL4028374 0.87 DGAT1 (0.40) DGAT1
SCHEMBL24410532 0.77 DGAT1 (0.36) DGAT1
SCHEMBL27777472 0.77 DGAT1 (0.54) DGAT1
SCHEMBL22572567 0.74 DGAT1 (0.52) DGAT1
SCHEMBL18559 0.74 DGAT1 (0.52) DGAT1
Hydrochloric Acid SCHEMBL23094114 0.72 DGAT1 (0.50) DGAT1
SCHEMBL1515542 0.72 DGAT1 (0.56) DGAT1
SCHEMBL8917215 0.72 DGAT1 (0.50) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113917598-A Low-loss micro-structural optical fiber and preparation method thereof 芮汉华 2022-01-11 CN claimed
US-12516062-B2 Agricultural or horticultural insecticide or animal ectoparasite or endoparasite control agent each comprising an imidazopyridazine compound having a substituted cyclopropane-oxadiazole group or a salt thereof as active ingredient, and method for using the insecticide or the control agent NIHON NOHYAKU CO., LTD. (JP) 2026-01-06 US disclosed
US-20250380697-A1 ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME KYUNG NONG CORPORATION (KR) 2025-12-18 US disclosed
US-12484581-B2 Agricultural or horticultural insecticide or animal ectoparasite or endoparasite control agent each comprising a condensed heterocyclic compound having a substituted cyclopropane-oxadiazole group or a salt thereof as active ingredient, and method for using the insecticide or the control agent NIHON NOHYAKU CO., LTD. (JP) 2025-12-02 US disclosed
US-20250282749-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-09-11 US disclosed
US-20250163048-A1 COMPOUNDS AND METHODS OF USE TANGO THERAPEUTICS, INC. 2025-05-22 US disclosed
EP-4469445-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
EP-4469455-A1 COMPOUNDS AND METHODS OF USE Tango Therapeutics, Inc. (US) 2024-12-04 EP disclosed
WO-2024005548-A1 ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME 주식회사 경농 2024-01-04 WO disclosed
US-20230339886-A1 REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2023-10-26 US disclosed
US-20100105711-A1 Organic Compounds NOVARTIS AG 2010-04-29 US disclosed
US-20100105711-A1 Organic Compounds NOVARTIS AG 2010-04-29 US disclosed
US-20100105711-A1 Organic Compounds NOVARTIS AG 2010-04-29 US disclosed
US-20100016296-A1 HETEROARYL COMPOUNDS AND USES THEREOF AVILA THERAPEUTICS, INC. (US) 2010-01-21 US disclosed
WO-2009080694-A1 THIAZOLE DERIVATIVES USED AS PI 3 KINASE INHIBITORS NOVARTIS AG (CH) 2009-07-02 WO disclosed
US-20090163469-A1 Organic Compounds NOVARTIS AG 2009-06-25 US disclosed
US-20090137588-A1 HETEROARYL COMPOUNDS AND USES THEREOF AVILA THERAPEUTICS, INC. (US) 2009-05-28 US disclosed
WO-2009051822-A1 HETEROARYL COMPOUNDS AND USES THEREOF AVILA THERAPEUTICS, INC. (US) 2009-04-23 WO disclosed
US-20050096354-A1 Process for the preparation of substituted aryl pyrazoles PFIZER, INC. (US) 2005-05-05 US disclosed
WO-2005023773-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED ARYL PYRAZOLES PFIZER LIMITED (GB) 2005-03-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230339886-A1 REV-ERB AGONISTS FOR THE TREATMENT OF TH17-MEDIATED INFLAMMATORY DISORDERS NR1H2, NR1H3, NR1D1 DGAT1 1987/4885
US-20050096354-A1 Process for the preparation of substituted aryl pyrazoles CYP3A5, DDT, CYP3A4 DGAT1 3812/4885
US-20250282749-A1 COMPOUNDS AND METHODS OF USE CYP1B1, CYP2C19, UGT1A1 DGAT1 4478/4885
US-20090137588-A1 HETEROARYL COMPOUNDS AND USES THEREOF ABCG2, CYP3A43, CYP3A5 DGAT1 2168/4885
US-20100105711-A1 Organic Compounds PIK3C3, PIK3CA, PIK3CD DGAT1 1321/4885
US-20100016296-A1 HETEROARYL COMPOUNDS AND USES THEREOF ABCG2, CYP3A43, CYP3A5 DGAT1 2168/4885
US-12484581-B2 Agricultural or horticultural insecticide or animal ectoparasite or endoparasite control agent each comprising a condensed heterocyclic compound having a substituted cyclopropane-oxadiazole group or a salt thereof as active ingredient, and method for using the insecticide or the control agent H1-3, H1-0, CBR3 DGAT1 2914/4885
US-20250380697-A1 ISOXAZOLINE DERIVATIVE COMPOUND AND INSECTICIDAL COMPOSITION COMPRISING SAME VIP, CASP7, CYP4X1 DGAT1 2541/4885
US-20250163048-A1 COMPOUNDS AND METHODS OF USE RB1, CYP1B1, REN DGAT1 4748/4885
US-20090163469-A1 Organic Compounds PIK3C3, PIK3CA, PIK3CD DGAT1 1188/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.